MYOZ3 and LDB3

Data Source:
HPRD (two hybrid, in vitro)

		MYOZ3	LDB3
Description		myozenin 3	LIM domain binding 3
Image		No pdb structure
GO Annotations	Cellular Component	Actin Cytoskeleton Z Disc	Stress Fiber Cytoskeleton Adherens Junction Z Disc Pseudopodium Filamentous Actin Perinuclear Region Of Cytoplasm
	Molecular Function	Actin Binding Protein Binding Telethonin Binding FATZ Binding	Actin Binding Protein Kinase C Binding Protein Binding Cytoskeletal Protein Binding Metal Ion Binding Muscle Alpha-actinin Binding
	Biological Process		Heart Development Actin Cytoskeleton Organization Sarcomere Organization Muscle Structure Development
Pathways
Drugs
Diseases			Distal muscular dystrophies, including: Welander distal myopathy (WDM); Tibial muscular dystrophy (TMD); Nonaka distal myopathy with rimmed vacuoles (DMRV); Miyoshi myopathy (MM); Laing myopathy (MPD1); Distal nebulin myopathy (DNM); Distal desminopathy (MFM1); alpha-B Crystallinopathy (MFM2); Distal myotilinopathy (MFM3); Distal zaspopathy (MFM4); Distal myopathy 3 (MPD2, VCPDM) Myofibrillar myopathies (MFM), including: Desminopathy (MFM1); alpha-B Crystallinopathy (MFM2); Myotilinopathy (MFM3); Zaspopathy (MFM4); Filaminopathy (MFM5); Bag3opathy
GWAS		Cholangiocarcinoma in primary sclerosing cholangitis ( 28779025) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908)	Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Heel bone mineral density ( 30598549) Plasma androstenedione levels in resected early stage-receptor positive breast cancer ( 28429243) Post bronchodilator FEV1 ( 26634245) Post bronchodilator FEV1/FVC ratio ( 26634245)
Interacting Genes		71 interacting genes: ABI2 ACTN1 ACTN2 AKIRIN2 ASPG ATXN1L BAG4 BCAS2 C10orf55 C10orf82 CCDC57 CREM CRLF3 DAZAP2 DMRT3 EFS ENKD1 EXOC8 FAM166B FAM168B FAM214B FHL3 FHL5 FLNC GCM2 GOLGA6A GOLGA6L9 HSF2BP KANK2 KRT34 KRT36 KRT75 KRTAP19-5 KRTAP19-6 KRTAP6-1 KRTAP7-1 KRTAP8-1 KYNU LDB3 LENG8 LMO2 LMO3 LMO4 LONRF1 MAPK6 MORN3 MRPL38 MYO15B NEK6 NUTF2 PDLIM3 PITX1 PM20D2 PPP3CA PPP3CB PRDM6 PSMB4 PTK6 RINT1 RNF125 RUSC1 TBX15 TCAP TEKT4 TRAPPC6A TSC1 TSSK3 UFSP1 YPEL3 ZNF620 ZNF688	7 interacting genes: ACTN2 ANKRD2 MYOZ1 MYOZ2 MYOZ3 TFCP2 TP53
Entrez ID		91977	11155
HPRD ID		17624	16172
Ensembl ID		ENSG00000164591	ENSG00000122367
Uniprot IDs		Q8TDC0	A0A0S2Z501 A0A0S2Z530 O75112
PDB IDs			1RGW 4YDP
Enriched GO Terms of Interacting Partners?
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