LDB3 and TFCP2

Data Source:
BioGRID (two hybrid)

		LDB3	TFCP2
Description		LIM domain binding 3	transcription factor CP2
Image			No pdb structure
GO Annotations	Cellular Component	Stress Fiber Cytoskeleton Adherens Junction Z Disc Pseudopodium Filamentous Actin Perinuclear Region Of Cytoplasm	Chromatin Nucleus Nucleoplasm Cytosol Protein-containing Complex
	Molecular Function	Actin Binding Protein Kinase C Binding Protein Binding Cytoskeletal Protein Binding Metal Ion Binding Muscle Alpha-actinin Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Transcription Factor Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Heart Development Actin Cytoskeleton Organization Sarcomere Organization Muscle Structure Development	Regulation Of Transcription By RNA Polymerase II MRNA Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs
Diseases		Distal muscular dystrophies, including: Welander distal myopathy (WDM); Tibial muscular dystrophy (TMD); Nonaka distal myopathy with rimmed vacuoles (DMRV); Miyoshi myopathy (MM); Laing myopathy (MPD1); Distal nebulin myopathy (DNM); Distal desminopathy (MFM1); alpha-B Crystallinopathy (MFM2); Distal myotilinopathy (MFM3); Distal zaspopathy (MFM4); Distal myopathy 3 (MPD2, VCPDM) Myofibrillar myopathies (MFM), including: Desminopathy (MFM1); alpha-B Crystallinopathy (MFM2); Myotilinopathy (MFM3); Zaspopathy (MFM4); Filaminopathy (MFM5); Bag3opathy
GWAS		Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Heel bone mineral density ( 30598549) Plasma androstenedione levels in resected early stage-receptor positive breast cancer ( 28429243) Post bronchodilator FEV1 ( 26634245) Post bronchodilator FEV1/FVC ratio ( 26634245)
Interacting Genes		7 interacting genes: ACTN2 ANKRD2 MYOZ1 MYOZ2 MYOZ3 TFCP2 TP53	74 interacting genes: ACAA1 ADPRH APBB1 ASAP3 BAG6 C19orf73 CA1 CAPN3 CASP8 CBX8 CDC73 COIL DNAJC27 DNAJC5B DPH1 E2F8 EAF1 EIF5B EPHA10 FAM120C FANCL FARS2 FBXL18 GPANK1 HAPLN2 HDAC1 HDAC2 IRAK1BP1 LDB3 LSM1 MAPK1 MAPK14 MAPK8 MOB3C MORF4L1 MRPL11 MRPL40 MVP NABP1 NEDD9 NFE4 NHSL2 NOM1 NPEPL1 PHF1 PHF21B PIMREG PITPNM1 PLCB1 POLL POLR3GL PPIG PPP1R1B PPP3R2 PSMD5 RBMS1 RNF2 RXRB SDCBP SHTN1 SIN3A STMN2 SUMO1 TCEA2 TDRD1 TLK1 TRAPPC12 TSPAN12 UBE2I UBP1 YJU2 YY1 ZCCHC10 ZCCHC12
Entrez ID		11155	7024
HPRD ID		16172	01790
Ensembl ID		ENSG00000122367	ENSG00000135457
Uniprot IDs		A0A0S2Z501 A0A0S2Z530 O75112	A0A024R120 Q12800
PDB IDs		1RGW 4YDP
Enriched GO Terms of Interacting Partners?
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