ZBED1 and TRAPPC2

Data Source:
BioGRID (affinity chromatography technology, two hybrid)

		ZBED1	TRAPPC2
Description		zinc finger BED-type containing 1	trafficking protein particle complex subunit 2
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Centrosome PML Body Nuclear Membrane	Golgi Membrane Nucleus Nucleoplasm Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum-Golgi Intermediate Compartment Cytosol TRAPP Complex Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Transcription Coregulator Activity Transcription Coactivator Activity Protein Binding SUMO Transferase Activity Identical Protein Binding Sequence-specific DNA Binding Metal Ion Binding Protein Dimerization Activity SUMO Ligase Activity Sequence-specific Double-stranded DNA Binding	Protein Binding Transcription Factor Binding Ion Channel Binding
	Biological Process	Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Viral Process Negative Regulation By Host Of Viral Genome Replication Positive Regulation Of Transcription By RNA Polymerase II Protein Autosumoylation	Skeletal System Development Regulation Of Transcription, DNA-templated Endoplasmic Reticulum To Golgi Vesicle-mediated Transport COPII Vesicle Coating
Pathways		SUMOylation of chromatin organization proteins	COPII-mediated vesicle transport RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases			Spondyloepiphyseal dysplasia tarda
GWAS
Interacting Genes		55 interacting genes: AMOTL2 ATRX C1orf109 CCDC13 CDC37 CTNNAL1 DGCR6 EFHC1 FABP4 FAM124B FANCG FNDC11 GGACT GORASP2 GPN1 GPSM1 KDM1A KIFC3 KLHL40 LCN2 LNX1 LRRC20 MAD2L2 MAGEB2 MKKS MLH1 MPST MYO15B NCDN NIF3L1 NIP7 NTAQ1 NUDT18 PAX6 PIAS2 PICK1 POLE2 POLR1C PRKAA1 PRKAR1A PSAP RENBP RIN1 SORBS3 SPEF1 SSX2 SUMO2 TRAPPC2 TRAPPC2B TRIML2 TTC23 TTR UBE2I UCHL5 USP2	37 interacting genes: ABRA CLIC1 CLIC2 DAPK1 EIF3C ENO1 ENO3 EPS15L1 HLA-E INCA1 JOSD2 KCTD1 LSM3 MBD3L1 MFHAS1 NICN1 NME4 NR5A1 PITX1 PYGM REPS1 SLC25A35 SNAPC5 TEPSIN TRAPPC3 TRAPPC3L TRAPPC4 TRAPPC5 TRAPPC6A TRAPPC6B TRAPPC9 UQCC2 ZBED1 ZBTB38 ZNF438 ZNF655 ZRANB1
Entrez ID		9189	6399
HPRD ID		02170	02189
Ensembl ID		ENSG00000214717	ENSG00000196459
Uniprot IDs		A0A024RBU4 O96006	P0DI81 P0DI82 Q6IBE5
PDB IDs		2CT5
Enriched GO Terms of Interacting Partners?
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