TRAPPC2 and ABRA

Data Source:
BioGRID (two hybrid)

		TRAPPC2	ABRA
Description		trafficking protein particle complex subunit 2	actin binding Rho activating protein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Nucleus Nucleoplasm Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum-Golgi Intermediate Compartment Cytosol TRAPP Complex Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm	Plasma Membrane Actin Cytoskeleton Sarcomere
	Molecular Function	Protein Binding Transcription Factor Binding Ion Channel Binding	Actin Binding Protein Binding
	Biological Process	Skeletal System Development Regulation Of Transcription, DNA-templated Endoplasmic Reticulum To Golgi Vesicle-mediated Transport COPII Vesicle Coating	Protein Import Into Nucleus Positive Regulation Of Rho Protein Signal Transduction Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of DNA-binding Transcription Factor Activity
Pathways		COPII-mediated vesicle transport RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases		Spondyloepiphyseal dysplasia tarda
GWAS			Dental caries ( 23259602) Epilepsy and lamotrigine-induced maculopapular eruptions ( 26220383) Intraocular pressure ( 31959993 30054594) Metabolite levels ( 23823483)
Interacting Genes		37 interacting genes: ABRA CLIC1 CLIC2 DAPK1 EIF3C ENO1 ENO3 EPS15L1 HLA-E INCA1 JOSD2 KCTD1 LSM3 MBD3L1 MFHAS1 NICN1 NME4 NR5A1 PITX1 PYGM REPS1 SLC25A35 SNAPC5 TEPSIN TRAPPC3 TRAPPC3L TRAPPC4 TRAPPC5 TRAPPC6A TRAPPC6B TRAPPC9 UQCC2 ZBED1 ZBTB38 ZNF438 ZNF655 ZRANB1	6 interacting genes: ABLIM2 ACTA1 ACTB ACTC1 PPP1R18 TRAPPC2
Entrez ID		6399	137735
HPRD ID		02189	11608
Ensembl ID		ENSG00000196459	ENSG00000174429
Uniprot IDs		P0DI81 P0DI82 Q6IBE5	Q8N0Z2
PDB IDs
Enriched GO Terms of Interacting Partners?
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