TRAPPC2 and EPS15L1

Data Source:
BioGRID (two hybrid)

		TRAPPC2	EPS15L1
Description		trafficking protein particle complex subunit 2	epidermal growth factor receptor pathway substrate 15 like 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Nucleus Nucleoplasm Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum-Golgi Intermediate Compartment Cytosol TRAPP Complex Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm	Nucleus Cytoplasm Cytosol Plasma Membrane Membrane Clathrin Coat Of Coated Pit
	Molecular Function	Protein Binding Transcription Factor Binding Ion Channel Binding	Calcium Ion Binding Protein Binding Cadherin Binding
	Biological Process	Skeletal System Development Regulation Of Transcription, DNA-templated Endoplasmic Reticulum To Golgi Vesicle-mediated Transport COPII Vesicle Coating	Endocytosis Endosomal Transport Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Membrane Organization
Pathways		COPII-mediated vesicle transport RAB GEFs exchange GTP for GDP on RABs	EGFR downregulation Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis
Drugs
Diseases		Spondyloepiphyseal dysplasia tarda
GWAS			Basophil count ( 32888494) Body size at age 10 ( 32376654) Eosinophil counts ( 32888494) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 32888494) Lymphocyte counts ( 29403010 32888494 27863252) Lymphocyte percentage of white cells ( 32888494 27863252) Monocyte count ( 32888494) Monocyte percentage of white cells ( 32888494 27863252) Multiple sclerosis ( 31604244 22190364 24076602) Neutrophil percentage of granulocytes ( 27863252) Neutrophil percentage of white cells ( 32888494 27863252) White blood cell count ( 32888494 27863252 21738480) White matter integrity ( 23218918)
Interacting Genes		37 interacting genes: ABRA CLIC1 CLIC2 DAPK1 EIF3C ENO1 ENO3 EPS15L1 HLA-E INCA1 JOSD2 KCTD1 LSM3 MBD3L1 MFHAS1 NICN1 NME4 NR5A1 PITX1 PYGM REPS1 SLC25A35 SNAPC5 TEPSIN TRAPPC3 TRAPPC3L TRAPPC4 TRAPPC5 TRAPPC6A TRAPPC6B TRAPPC9 UQCC2 ZBED1 ZBTB38 ZNF438 ZNF655 ZRANB1	15 interacting genes: AGFG1 AGFG2 EPN1 FCHO1 FCHO2 GNG5 ITSN1 ITSN2 LRRC7 NDC80 SGIP1 STON2 TRAPPC2 TRAPPC2B UBC
Entrez ID		6399	58513
HPRD ID		02189	09445
Ensembl ID		ENSG00000196459	ENSG00000127527
Uniprot IDs		P0DI81 P0DI82 Q6IBE5	A0A024R7G6 Q9UBC2
PDB IDs
Enriched GO Terms of Interacting Partners?
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