AP4M1 and PMPCB

Data Source:
BioGRID (affinity chromatography technology)

		AP4M1	PMPCB
Description		adaptor related protein complex 4 subunit mu 1	peptidase, mitochondrial processing subunit beta
Image			No pdb structure
GO Annotations	Cellular Component	Early Endosome Trans-Golgi Network Cytosol AP-4 Adaptor Complex Clathrin Adaptor Complex Cytoplasmic Vesicle Endosome Lumen Trans-Golgi Network Membrane Intracellular Membrane-bounded Organelle Extracellular Exosome	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Processing Peptidase Complex
	Molecular Function	Protein Binding Protein Domain Specific Binding	Metalloendopeptidase Activity Metal Ion Binding
	Biological Process	Protein Targeting Protein Targeting To Lysosome Intracellular Protein Transport Golgi To Endosome Transport Protein Localization Vesicle-mediated Transport Golgi To Lysosome Transport Protein Localization To Basolateral Plasma Membrane	Protein Processing Involved In Protein Targeting To Mitochondrion Mitochondrial Calcium Ion Transmembrane Transport
Pathways		Lysosome Vesicle Biogenesis	Mitochondrial protein import Processing of SMDT1
Drugs
Diseases		Cerebral palsy
GWAS		Brain morphology (MOSTest) ( 32665545) Refractive error ( 32231278) Subcortical volume (MOSTest) ( 32665545)	Diverticular disease ( 30177863)
Interacting Genes		14 interacting genes: AP4B1 ARF1 CACNG3 CD63 CHTF8 DDX52 FNTA GRID2 GRIN2A GRIN2B LAMP2 TGOLN2 USP47 ZBTB22	5 interacting genes: FXN MARK3 NPSR1 PMPCA PTGER4
Entrez ID		9179	9512
HPRD ID		03803	07539
Ensembl ID		ENSG00000221838	ENSG00000105819
Uniprot IDs		C9JC87 O00189	B3KM34 O75439 Q96CP5
PDB IDs		3L81 4MDR
Enriched GO Terms of Interacting Partners?
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