SCAF11 and SRSF2

Data Source:
HPRD (two hybrid, in vitro, in vivo)

		SCAF11	SRSF2
Description		SR-related CTD associated factor 11	serine and arginine rich splicing factor 2
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Nucleolus Nuclear Body	Nucleus Nucleoplasm Cytoplasm Cytosol PML Body Nuclear Speck
	Molecular Function	RNA Binding Protein Binding Metal Ion Binding	Transcription Corepressor Activity RNA Binding Protein Binding
	Biological Process	Spliceosomal Complex Assembly RNA Splicing, Via Transesterification Reactions MRNA Processing RNA Splicing	MRNA Splicing, Via Spliceosome MRNA Processing RNA Export From Nucleus MRNA Export From Nucleus RNA Splicing MRNA 3'-end Processing Negative Regulation Of Transcription, DNA-templated
Pathways			Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination
Drugs
Diseases
GWAS		Coronary artery disease ( 29212778) Fish- and plant-related diet ( 32066663) Hemoglobin levels ( 32327693) Morning person ( 30696823) Multiple sclerosis ( 31604244) Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892) Refractive error ( 32231278)
Interacting Genes		11 interacting genes: ATXN1L PSEN1 SNRNP70 SRPK1 SRSF1 SRSF2 SRSF3 SRSF4 STAT3 SUMO2 U2AF2	34 interacting genes: ADAP1 BARD1 CCNL1 CCNL2 CDK12 CDK6 CEP72 CIR1 CSNK2A1 FUS GEMIN2 GOLGA2 KAT5 KRT31 KRT40 LIG4 LZTS2 NCF1 PRCC SCAF11 SNRNP70 SREK1 SRPK2 SRSF11 SRSF3 SRSF4 TCF4 TRA2B TRIM27 U2AF1 UBQLN4 YTHDC1 ZRANB2 ZRSR2
Entrez ID		9169	6427
HPRD ID		04720	02888
Ensembl ID		ENSG00000139218	ENSG00000161547
Uniprot IDs		Q99590	A0A024R8U5 Q01130 Q53FN0
PDB IDs			2KN4 2LEA 2LEB 2LEC
Enriched GO Terms of Interacting Partners?
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