SCAF11 and SRSF1

Data Source:
HPRD (two hybrid)

		SCAF11	SRSF1
Description		SR-related CTD associated factor 11	serine and arginine rich splicing factor 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Nucleolus Nuclear Body	Nucleus Nucleoplasm Cytoplasm Nuclear Speck Exon-exon Junction Complex Catalytic Step 2 Spliceosome
	Molecular Function	RNA Binding Protein Binding Metal Ion Binding	RNA Binding MRNA Binding Protein Binding DNA Topoisomerase Binding
	Biological Process	Spliceosomal Complex Assembly RNA Splicing, Via Transesterification Reactions MRNA Processing RNA Splicing	Alternative MRNA Splicing, Via Spliceosome MRNA 5'-splice Site Recognition MRNA Splicing, Via Spliceosome MRNA Splice Site Selection MRNA Processing RNA Export From Nucleus MRNA Export From Nucleus MRNA 3'-end Processing
Pathways			Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination
Drugs			Copper
Diseases
GWAS		Coronary artery disease ( 29212778) Fish- and plant-related diet ( 32066663) Hemoglobin levels ( 32327693) Morning person ( 30696823) Multiple sclerosis ( 31604244) Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892) Refractive error ( 32231278)	Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223)
Interacting Genes		11 interacting genes: ATXN1L PSEN1 SNRNP70 SRPK1 SRSF1 SRSF2 SRSF3 SRSF4 STAT3 SUMO2 U2AF2	43 interacting genes: AKAP17A APP BCL10 C1QBP CACNA1A CD8A CDC42 CDK12 CDK6 CLK1 DIDO1 DYRK1A GEMIN2 HIPK3 HNRNPA0 LNX1 LUC7L3 NFYA NXF1 PPARG PRPF4 PRPF4B PSIP1 RNPS1 SCAF11 SNRNP70 SREK1 SRPK1 SRPK2 SRSF10 SRSF11 SRSF4 SRSF5 TCERG1 TNPO3 TOP1 TP53 TRA2B U2AF1 U2AF2 XBP1 YTHDC1 ZRSR2
Entrez ID		9169	6426
HPRD ID		04720	02887
Ensembl ID		ENSG00000139218	ENSG00000136450
Uniprot IDs		Q99590	Q07955 Q59FA2
PDB IDs			1X4A 2M7S 2M8D 2O3D 3BEG 4C0O
Enriched GO Terms of Interacting Partners?
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