SRSF1 and PSIP1

Data Source:
HPRD (in vivo, in vitro)

		SRSF1	PSIP1
Description		serine and arginine rich splicing factor 1	PC4 and SFRS1 interacting protein 1
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Nuclear Speck Exon-exon Junction Complex Catalytic Step 2 Spliceosome	Nucleus Nucleoplasm Cytosol Transcriptionally Active Chromatin
	Molecular Function	RNA Binding MRNA Binding Protein Binding DNA Topoisomerase Binding	Double-stranded DNA Binding Transcription Coregulator Activity RNA Binding Protein Binding Supercoiled DNA Binding
	Biological Process	Alternative MRNA Splicing, Via Spliceosome MRNA 5'-splice Site Recognition MRNA Splicing, Via Spliceosome MRNA Splice Site Selection MRNA Processing RNA Export From Nucleus MRNA Export From Nucleus MRNA 3'-end Processing	MRNA 5'-splice Site Recognition Regulation Of Transcription By RNA Polymerase II Response To Oxidative Stress Response To Heat Nuclear Transport Establishment Of Integrated Proviral Latency
Pathways		Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination	Integration of provirus 2-LTR circle formation Integration of viral DNA into host genomic DNA Autointegration results in viral DNA circles APOBEC3G mediated resistance to HIV-1 infection Vpr-mediated nuclear import of PICs
Drugs		Copper
Diseases
GWAS		Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223)
Interacting Genes		43 interacting genes: AKAP17A APP BCL10 C1QBP CACNA1A CD8A CDC42 CDK12 CDK6 CLK1 DIDO1 DYRK1A GEMIN2 HIPK3 HNRNPA0 LNX1 LUC7L3 NFYA NXF1 PPARG PRPF4 PRPF4B PSIP1 RNPS1 SCAF11 SNRNP70 SREK1 SRPK1 SRPK2 SRSF10 SRSF11 SRSF4 SRSF5 TCERG1 TNPO3 TOP1 TP53 TRA2B U2AF1 U2AF2 XBP1 YTHDC1 ZRSR2	13 interacting genes: CASP3 CASP7 CDC42 CSNK2A1 HCFC1 HMGA1 HMGA2 MAPK6 MTDH SP1 SRSF1 SUB1 SUMO1
Entrez ID		6426	11168
HPRD ID		02887	04688
Ensembl ID		ENSG00000136450	ENSG00000164985
Uniprot IDs		Q07955 Q59FA2	O75475
PDB IDs		1X4A 2M7S 2M8D 2O3D 3BEG 4C0O	1Z9E 2B4J 2M16 2MSR 2MTN 2N3A 3F9K 3HPG 3HPH 3U88 3ZEH 4FU6 5N88 5OYM 5YI9 6EMO 6EMP 6EMQ 6EMR 6S01 6TRJ 6TVM 6Z2Y
Enriched GO Terms of Interacting Partners?
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