ATG3 and ATG7

Data Source:
HPRD (in vivo)

		ATG3	ATG7
Description		autophagy related 3	autophagy related 7
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasmic Ubiquitin Ligase Complex Cytosol	Phagophore Assembly Site Extracellular Region Cytoplasm Cytosol Axoneme Axon Secretory Granule Lumen Ficolin-1-rich Granule Lumen
	Molecular Function	Protein Binding Atg8 Ligase Activity Atg12 Transferase Activity Ubiquitin-like Protein Transferase Activity Enzyme Binding	Protein Binding Transcription Factor Binding Atg12 Activating Enzyme Activity Atg8 Activating Enzyme Activity Protein Homodimerization Activity
	Biological Process	Autophagosome Assembly Autophagy Of Mitochondrion Cellular Protein Modification Process Protein Targeting To Membrane Macroautophagy Protein Ubiquitination Protein Phosphopantetheinylation Mitochondrial Fragmentation Involved In Apoptotic Process Autophagy Of Nucleus Negative Regulation Of Phagocytosis Regulation Of Cilium Assembly	Autophagosome Assembly Autophagy Of Mitochondrion Protein Lipidation C-terminal Protein Lipidation Autophagy Cellular Response To Nitrogen Starvation Aging Cellular Response To Starvation Response To Glucose Protein Transport Macroautophagy Protein Phosphopantetheinylation Positive Regulation Of Protein Modification Process Protein Modification By Small Protein Conjugation Piecemeal Microautophagy Of The Nucleus Suppression By Virus Of Host Autophagy Regulation Of Circadian Rhythm Positive Regulation Of Apoptotic Process Neutrophil Degranulation Late Nucleophagy Positive Regulation Of Protein Catabolic Process Rhythmic Process Defense Response To Virus Chaperone-mediated Autophagy Cellular Response To Morphine Cellular Response To Hyperoxia Positive Regulation By Symbiont Of Host Autophagy Negative Regulation Of Mitochondrial DNA Replication Response To Fluoride Negative Regulation Of Oxidative Stress-induced Neuron Death
Pathways		Macroautophagy	Macroautophagy Macroautophagy Neutrophil degranulation Signaling by BRAF and RAF fusions Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Asthma (childhood onset) ( 23829686)	Body fat mass ( 28552196) Body size at age 10 ( 32376654) Circulating chemerin levels ( 25521368) HDL cholesterol ( 24097068 25961943) HDL cholesterol levels ( 28334899) Heel bone mineral density ( 28869591) Male-pattern baldness ( 28196072) Pulse pressure ( 30578418) Relative hand skill in reading disability ( 24068947) Small vessel stroke ( 29123153) Systolic blood pressure ( 27618447 27618452 30578418)
Interacting Genes		7 interacting genes: ATG12 ATG7 BECN1 GABARAP GABARAPL2 MAP1LC3B MOB2	10 interacting genes: APP ATG10 ATG12 ATG3 EEF1D GABARAP GABARAPL2 IRF2 MAP1LC3A MAP1LC3B
Entrez ID		64422	10533
HPRD ID		10654	12293
Ensembl ID		ENSG00000144848	ENSG00000197548
Uniprot IDs		Q9NT62	B3KQM6 O95352
PDB IDs		4NAW
Enriched GO Terms of Interacting Partners?
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