CBFA2T2 and SIKE1

		CBFA2T2	SIKE1
Description		CBFA2/RUNX1 partner transcriptional co-repressor 2	suppressor of IKBKE 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Cytosol
	Molecular Function	Transcription Corepressor Activity Protein Binding Metal Ion Binding	Protein Binding Protein Kinase Binding Small GTPase Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Transcription, DNA-templated Positive Regulation Of Neuron Projection Development Negative Regulation Of Neuron Projection Development Negative Regulation Of Notch Signaling Pathway Negative Regulation Of Transcription, DNA-templated Intestinal Epithelial Cell Differentiation
Pathways			TRAF3-dependent IRF activation pathway TRAF6 mediated IRF7 activation
Drugs
Diseases
GWAS		Height ( 28552196) Triglyceride levels ( 32203549)
Interacting Genes		34 interacting genes: APP ATN1 ATXN1L BAG4 CBFA2T3 CBFB CEP83 FBXL19 GTF2E1 ID3 KIFC3 KRTAP13-2 LBP MAGEA6 MDFI NCOR1 NCOR2 NEUROG1 NOTCH3 NTAQ1 PDP1 PHAF1 PRDM14 PRDM6 RERE RUNX1 SIKE1 SIN3A SORBS3 TAL2 TCF4 TCP1 ZC2HC1A ZNF652	13 interacting genes: CBFA2T2 CENPQ CTAG1A CTAG1B IKBKE NTAQ1 SCOC STRN3 STX11 TBK1 TXLNA TXLNB ZC2HC1C
Entrez ID		9139	80143
HPRD ID		04721	07958
Ensembl ID		ENSG00000078699	ENSG00000052723
Uniprot IDs		O43439	Q9BRV8
PDB IDs			6AKK 6AKL 6AKM
Enriched GO Terms of Interacting Partners?
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