CBFA2T2 and PDP1

Data Source:
BioGRID (two hybrid)

		CBFA2T2	PDP1
Description		CBFA2/RUNX1 partner transcriptional co-repressor 2	pyruvate dehydrogenase phosphatase catalytic subunit 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Mitochondrion Mitochondrial Matrix
	Molecular Function	Transcription Corepressor Activity Protein Binding Metal Ion Binding	Protein Serine/threonine Phosphatase Activity Magnesium-dependent Protein Serine/threonine Phosphatase Activity [pyruvate Dehydrogenase (lipoamide)] Phosphatase Activity Protein Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Transcription, DNA-templated Positive Regulation Of Neuron Projection Development Negative Regulation Of Neuron Projection Development Negative Regulation Of Notch Signaling Pathway Negative Regulation Of Transcription, DNA-templated Intestinal Epithelial Cell Differentiation	Protein Dephosphorylation Regulation Of Acetyl-CoA Biosynthetic Process From Pyruvate Peptidyl-threonine Dephosphorylation Positive Regulation Of Pyruvate Dehydrogenase Activity
Pathways			Regulation of pyruvate dehydrogenase (PDH) complex
Drugs
Diseases			Pyruvate dehydrogenase complex deficiency; X-linked Leigh syndrome
GWAS		Height ( 28552196) Triglyceride levels ( 32203549)
Interacting Genes		34 interacting genes: APP ATN1 ATXN1L BAG4 CBFA2T3 CBFB CEP83 FBXL19 GTF2E1 ID3 KIFC3 KRTAP13-2 LBP MAGEA6 MDFI NCOR1 NCOR2 NEUROG1 NOTCH3 NTAQ1 PDP1 PHAF1 PRDM14 PRDM6 RERE RUNX1 SIKE1 SIN3A SORBS3 TAL2 TCF4 TCP1 ZC2HC1A ZNF652	10 interacting genes: ACAT1 CBFA2T2 EGFR FGFR1 INCA1 KRTAP6-2 MEOX2 PDHA1 PRKCD SIRT3
Entrez ID		9139	54704
HPRD ID		04721	16185
Ensembl ID		ENSG00000078699	ENSG00000164951
Uniprot IDs		O43439	A0A024R9C0 Q6P1N1 Q9P0J1
PDB IDs
Enriched GO Terms of Interacting Partners?
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