SIKE1 and STRN3

		SIKE1	STRN3
Description		suppressor of IKBKE 1	striatin 3
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GO Annotations	Cellular Component	Cytosol	Nucleoplasm Golgi Apparatus Plasma Membrane Dendrite Protein-containing Complex Neuronal Cell Body FAR/SIN/STRIPAK Complex
	Molecular Function	Protein Binding Protein Kinase Binding Small GTPase Binding	Protein Binding Calmodulin Binding Small GTPase Binding Protein-containing Complex Binding Protein Phosphatase 2A Binding Armadillo Repeat Domain Binding
	Biological Process		Response To Estradiol Negative Regulation Of Intracellular Estrogen Receptor Signaling Pathway Negative Regulation Of Transcription, DNA-templated
Pathways		TRAF3-dependent IRF activation pathway TRAF6 mediated IRF7 activation
Drugs
Diseases
GWAS			Brain morphology (MOSTest) ( 32665545) Mean platelet volume ( 32888494) Platelet count ( 32888494)
Interacting Genes		13 interacting genes: CBFA2T2 CENPQ CTAG1A CTAG1B IKBKE NTAQ1 SCOC STRN3 STX11 TBK1 TXLNA TXLNB ZC2HC1C	10 interacting genes: CALM1 GABARAPL1 MOB1A NR3C1 PPP2R1A PPP2R1B PPP2R2A SIKE1 SLC2A4 TCEANC
Entrez ID		80143	29966
HPRD ID		07958	11613
Ensembl ID		ENSG00000052723	ENSG00000196792
Uniprot IDs		Q9BRV8	Q13033
PDB IDs		6AKK 6AKL 6AKM	4N6J 6AKL 6IUR
Enriched GO Terms of Interacting Partners?
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