ZNF598 and DBN1

Data Source:
HPRD (two hybrid)

		ZNF598	DBN1
Description		zinc finger protein 598, E3 ubiquitin ligase	drebrin 1
Image		No pdb structure
GO Annotations	Cellular Component		Cytoplasm Cytoskeleton Actin Filament Plasma Membrane Gap Junction Postsynaptic Density Actin Cytoskeleton Lamellipodium Dendrite Growth Cone Site Of Polarized Growth Cortical Cytoskeleton Cortical Actin Cytoskeleton Actomyosin Postsynaptic Membrane Glutamatergic Synapse Postsynaptic Cytosol
	Molecular Function	RNA Binding Protein Binding Ribosome Binding Metal Ion Binding Ubiquitin Protein Ligase Activity	Actin Binding Protein Binding Profilin Binding Cadherin Binding Actin Filament Binding
	Biological Process	Protein Monoubiquitination Protein Ubiquitination Rescue Of Stalled Ribosome	In Utero Embryonic Development Actin Filament Organization Cell Communication By Chemical Coupling Cell Communication By Electrical Coupling Regulation Of Actin Filament Polymerization Positive Regulation Of Synaptic Plasticity Maintenance Of Protein Location In Cell Positive Regulation Of Axon Extension Regulation Of Neuronal Synaptic Plasticity Neuron Projection Morphogenesis Regulation Of Dendrite Development Cytoplasmic Sequestering Of Protein Positive Regulation Of Dendritic Spine Morphogenesis Neural Precursor Cell Proliferation Postsynaptic Actin Cytoskeleton Organization Positive Regulation Of Receptor Localization To Synapse
Pathways
Drugs
Diseases
GWAS			Activated partial thromboplastin time ( 22703881) Extremely high intelligence ( 29520040) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		3 interacting genes: CDA DBN1 UBE2D1	27 interacting genes: ACD BAK1 BTRC CDK2AP2 DNMBP DUSP23 ESR1 FHL1 HOMER2 MAP1LC3B MAPK6 MEST NIPBL NUDT21 NUDT3 PFN1 POT1 PTEN RABGAP1L SNUPN SUPT5H TAB1 TERF1 TINF2 TPT1 UBE2D3 ZNF598
Entrez ID		90850	1627
HPRD ID		11732	00545
Ensembl ID		ENSG00000167962	ENSG00000113758
Uniprot IDs		Q86UK7	Q16643
PDB IDs			5Y1Z 5ZZ9
Enriched GO Terms of Interacting Partners?
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