DBN1 and DNMBP

Data Source:
HPRD (in vitro)

		DBN1	DNMBP
Description		drebrin 1	dynamin binding protein
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GO Annotations	Cellular Component	Cytoplasm Cytoskeleton Actin Filament Plasma Membrane Gap Junction Postsynaptic Density Actin Cytoskeleton Lamellipodium Dendrite Growth Cone Site Of Polarized Growth Cortical Cytoskeleton Cortical Actin Cytoskeleton Actomyosin Postsynaptic Membrane Glutamatergic Synapse Postsynaptic Cytosol	Golgi Apparatus Golgi Stack Cytoskeleton Cell-cell Junction Synapse Presynapse
	Molecular Function	Actin Binding Protein Binding Profilin Binding Cadherin Binding Actin Filament Binding	Guanyl-nucleotide Exchange Factor Activity Protein Binding
	Biological Process	In Utero Embryonic Development Actin Filament Organization Cell Communication By Chemical Coupling Cell Communication By Electrical Coupling Regulation Of Actin Filament Polymerization Positive Regulation Of Synaptic Plasticity Maintenance Of Protein Location In Cell Positive Regulation Of Axon Extension Regulation Of Neuronal Synaptic Plasticity Neuron Projection Morphogenesis Regulation Of Dendrite Development Cytoplasmic Sequestering Of Protein Positive Regulation Of Dendritic Spine Morphogenesis Neural Precursor Cell Proliferation Postsynaptic Actin Cytoskeleton Organization Positive Regulation Of Receptor Localization To Synapse	Aging Regulation Of Cell Shape Intracellular Signal Transduction Regulation Of Catalytic Activity
Pathways
Drugs
Diseases
GWAS		Activated partial thromboplastin time ( 22703881) Extremely high intelligence ( 29520040) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Stent thrombosis in response to clopidogrel treatment ( 32472697)
Interacting Genes		27 interacting genes: ACD BAK1 BTRC CDK2AP2 DNMBP DUSP23 ESR1 FHL1 HOMER2 MAP1LC3B MAPK6 MEST NIPBL NUDT21 NUDT3 PFN1 POT1 PTEN RABGAP1L SNUPN SUPT5H TAB1 TERF1 TINF2 TPT1 UBE2D3 ZNF598	20 interacting genes: ACTA1 ARHGAP17 BUB1B CDC42 CNN1 CYFIP2 DBN1 DNM1 ENAH EVL FASLG HSPA1B KHDRBS1 NCKAP1 RAC1 RAPH1 VASP WASF1 WASL WIPF2
Entrez ID		1627	23268
HPRD ID		00545	10918
Ensembl ID		ENSG00000113758	ENSG00000107554
Uniprot IDs		Q16643	A0A1B0GTX1 A0A1C7CYY6 B3KY33 Q6XZF7
PDB IDs		5Y1Z 5ZZ9	1UG1 1UHC 4CC2 4CC3 4CC4 4CC7 4GLM
Enriched GO Terms of Interacting Partners?
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