DBN1 and ZNF598

Data Source:
HPRD (two hybrid)

		DBN1	ZNF598
Description		drebrin 1	zinc finger protein 598, E3 ubiquitin ligase
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytoskeleton Actin Filament Plasma Membrane Gap Junction Postsynaptic Density Actin Cytoskeleton Lamellipodium Dendrite Growth Cone Site Of Polarized Growth Cortical Cytoskeleton Cortical Actin Cytoskeleton Actomyosin Postsynaptic Membrane Glutamatergic Synapse Postsynaptic Cytosol
	Molecular Function	Actin Binding Protein Binding Profilin Binding Cadherin Binding Actin Filament Binding	RNA Binding Protein Binding Ribosome Binding Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	In Utero Embryonic Development Actin Filament Organization Cell Communication By Chemical Coupling Cell Communication By Electrical Coupling Regulation Of Actin Filament Polymerization Positive Regulation Of Synaptic Plasticity Maintenance Of Protein Location In Cell Positive Regulation Of Axon Extension Regulation Of Neuronal Synaptic Plasticity Neuron Projection Morphogenesis Regulation Of Dendrite Development Cytoplasmic Sequestering Of Protein Positive Regulation Of Dendritic Spine Morphogenesis Neural Precursor Cell Proliferation Postsynaptic Actin Cytoskeleton Organization Positive Regulation Of Receptor Localization To Synapse	Protein Monoubiquitination Protein Ubiquitination Rescue Of Stalled Ribosome
Pathways
Drugs
Diseases
GWAS		Activated partial thromboplastin time ( 22703881) Extremely high intelligence ( 29520040) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		27 interacting genes: ACD BAK1 BTRC CDK2AP2 DNMBP DUSP23 ESR1 FHL1 HOMER2 MAP1LC3B MAPK6 MEST NIPBL NUDT21 NUDT3 PFN1 POT1 PTEN RABGAP1L SNUPN SUPT5H TAB1 TERF1 TINF2 TPT1 UBE2D3 ZNF598	3 interacting genes: CDA DBN1 UBE2D1
Entrez ID		1627	90850
HPRD ID		00545	11732
Ensembl ID		ENSG00000113758	ENSG00000167962
Uniprot IDs		Q16643	Q86UK7
PDB IDs		5Y1Z 5ZZ9
Enriched GO Terms of Interacting Partners?
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