CADM3 and SEC11C

Data Source:
BioGRID (two hybrid)

		CADM3	SEC11C
Description		cell adhesion molecule 3	SEC11 homolog C, signal peptidase complex subunit
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Cell-cell Junction Integral Component Of Membrane	Signal Peptidase Complex Endoplasmic Reticulum Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding Protein Homodimerization Activity	Serine-type Endopeptidase Activity Protein Binding Peptidase Activity
	Biological Process	Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Adherens Junction Organization	Signal Peptide Processing
Pathways		Adherens junctions interactions Nectin/Necl trans heterodimerization	SRP-dependent cotranslational protein targeting to membrane Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) Synthesis, secretion, and deacylation of Ghrelin
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29679657) Asthma ( 32296059) Bipolar disorder and eating disorder ( 26433762) Inflammatory biomarkers ( 22291609) Neutrophil count in HIV-infection ( 25884002)	Alzheimer's disease (age of onset) ( 22005931) Chronotype ( 30696823) Morning person ( 30696823)
Interacting Genes		1 interacting genes: SEC11C	23 interacting genes: BTN2A2 C2 CADM3 GLP1R HMOX1 MFF PLPP6 PRSS23 RTP2 SCD SELENOM SERP1 STX12 TMEM128 TMEM243 TMEM254 TMEM42 TREX1 TSNARE1 UBE2J1 VAMP1 VAMP4 VAPA
Entrez ID		57863	90701
HPRD ID		13733	15310
Ensembl ID		ENSG00000162706	ENSG00000166562
Uniprot IDs		Q8N126	K7EJQ7 Q9BY50
PDB IDs		1Z9M
Enriched GO Terms of Interacting Partners?
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