RPL14 and TLE6

Data Source:
BioGRID (two hybrid)

		RPL14	TLE6
Description		ribosomal protein L14	TLE family member 6, subcortical maternal complex member
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol Postsynaptic Density Membrane Cytosolic Large Ribosomal Subunit Extracellular Exosome	Nucleus Transcription Regulator Complex Cell Cortex Protein-containing Complex Subcortical Maternal Complex
	Molecular Function	RNA Binding Structural Constituent Of Ribosome Protein Binding Cadherin Binding	Transcription Corepressor Activity Protein Binding Repressing Transcription Factor Binding
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay RRNA Processing Translation Translational Initiation SRP-dependent Cotranslational Protein Targeting To Membrane Viral Transcription Ribosomal Large Subunit Biogenesis	Negative Regulation Of Transcription By RNA Polymerase II Actin Filament Organization Positive Regulation Of Embryonic Development Establishment Of Spindle Localization Regulation Of Cell Division Endoplasmic Reticulum Localization Mitochondrion Localization Embryonic Process Involved In Female Pregnancy Negative Regulation Of Canonical Wnt Signaling Pathway
Pathways		L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis Major pathway of rRNA processing in the nucleolus and cytosol Formation of a pool of free 40S subunits GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs		Artenimol
Diseases
GWAS		Neuroticism ( 29255261)
Interacting Genes		7 interacting genes: FBXO7 KCNK4 KLF10 PEX5 PHLDA1 PTEN TLE6	4 interacting genes: FOXG1 RIPK3 RPL14 TRIM54
Entrez ID		9045	79816
HPRD ID		10617	18195
Ensembl ID		ENSG00000188846	ENSG00000104953
Uniprot IDs		P50914	Q6PJM9 Q9H808
PDB IDs		4UG0 4V6X 5AJ0 5LKS 5T2C 6EK0 6IP5 6IP6 6IP8 6LQM 6LSR 6LSS 6LU8 6OLE 6OLF 6OLG 6OLI 6OLZ 6OM0 6OM7 6QZP 6W6L 6XA1 6Y0G 6Y2L 6Y57 6Y6X 6Z6L 6Z6M 6Z6N 6ZM7 6ZME 6ZMI 6ZMO
Enriched GO Terms of Interacting Partners?
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