RPL14 and KCNK4

Data Source:
BioGRID (two hybrid)

		RPL14	KCNK4
Description		ribosomal protein L14	potassium two pore domain channel subfamily K member 4
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GO Annotations	Cellular Component	Cytosol Postsynaptic Density Membrane Cytosolic Large Ribosomal Subunit Extracellular Exosome	Plasma Membrane Integral Component Of Plasma Membrane Potassium Channel Complex
	Molecular Function	RNA Binding Structural Constituent Of Ribosome Protein Binding Cadherin Binding	Voltage-gated Ion Channel Activity Potassium Channel Activity Potassium Ion Leak Channel Activity Temperature-gated Cation Channel Activity Mechanosensitived Potassium Channel Activity
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay RRNA Processing Translation Translational Initiation SRP-dependent Cotranslational Protein Targeting To Membrane Viral Transcription Ribosomal Large Subunit Biogenesis	Potassium Ion Transport Memory Sensory Perception Of Pain Stabilization Of Membrane Potential Regulation Of Ion Transmembrane Transport Sensory Perception Of Temperature Stimulus Detection Of Mechanical Stimulus Involved In Sensory Perception Of Touch Cellular Response To Mechanical Stimulus Cellular Response To Fatty Acid Cellular Response To Alkaline PH Cellular Response To Temperature Stimulus Potassium Ion Transmembrane Transport
Pathways		L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis Major pathway of rRNA processing in the nucleolus and cytosol Formation of a pool of free 40S subunits GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)	TWIK related potassium channel (TREK) Phase 4 - resting membrane potential
Drugs		Artenimol
Diseases
GWAS		Neuroticism ( 29255261)	Crohn's disease ( 28067908) Sarcoidosis ( 22837380) Vitiligo ( 27723757)
Interacting Genes		7 interacting genes: FBXO7 KCNK4 KLF10 PEX5 PHLDA1 PTEN TLE6	3 interacting genes: DIDO1 ORMDL1 RPL14
Entrez ID		9045	50801
HPRD ID		10617	12037
Ensembl ID		ENSG00000188846	ENSG00000182450
Uniprot IDs		P50914	A0A024R5C7 Q2YDA1 Q9NYG8
PDB IDs		4UG0 4V6X 5AJ0 5LKS 5T2C 6EK0 6IP5 6IP6 6IP8 6LQM 6LSR 6LSS 6LU8 6OLE 6OLF 6OLG 6OLI 6OLZ 6OM0 6OM7 6QZP 6W6L 6XA1 6Y0G 6Y2L 6Y57 6Y6X 6Z6L 6Z6M 6Z6N 6ZM7 6ZME 6ZMI 6ZMO	3UM7 4I9W 4RUE 4RUF 4WFE 4WFF 4WFG 4WFH
Enriched GO Terms of Interacting Partners?
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