TMEM41A and FA2H

Data Source:
BioGRID (two hybrid)

		TMEM41A	FA2H
Description		transmembrane protein 41A	fatty acid 2-hydroxylase
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Integral Component Of Membrane	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding	Iron Ion Binding Protein Binding Heme Binding Fatty Acid Alpha-hydroxylase Activity
	Biological Process		Sebaceous Gland Cell Differentiation Fatty Acid Metabolic Process Fatty Acid Biosynthetic Process Glucosylceramide Biosynthetic Process Galactosylceramide Biosynthetic Process Sphingolipid Biosynthetic Process Lipid Modification Central Nervous System Myelin Maintenance Peripheral Nervous System Myelin Maintenance Regulation Of Cell Population Proliferation Regulation Of Hair Cycle Plasma Membrane Raft Organization Ceramide Biosynthetic Process Establishment Of Skin Barrier
Pathways			Sphingolipid de novo biosynthesis
Drugs
Diseases
GWAS			General cognitive ability ( 25383866) Pancreatic cancer ( 25086665) White matter lesion progression (adjusted for white matter lesion burden at baseline) ( 26451028)
Interacting Genes		9 interacting genes: CYB5B FA2H FXYD6-FXYD2 KASH5 LMNA LPAR3 NOTCH2NLA PTPN1 STX1A	31 interacting genes: AQP6 ARMC12 ASGR2 CD79A CREB3 CREB3L1 DLG2 EBP ELOVL4 ERGIC3 ERLIN1 FAM209A FCER1G GPR152 GPR37 GPX8 LMNA MARCHF8 MSR1 PEX12 PGRMC2 RIC3 SGPL1 SLC10A1 SLC10A6 SYT2 TLCD4 TMEM14B TMEM41A TMX2 UBQLN4
Entrez ID		90407	79152
HPRD ID		15539	16873
Ensembl ID		ENSG00000163900	ENSG00000103089
Uniprot IDs		Q96HV5	Q7L5A8
PDB IDs
Enriched GO Terms of Interacting Partners?
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