BAZ1B and SMARCA5

Data Source:
HPRD (in vitro, in vivo)

		BAZ1B	SMARCA5
Description		bromodomain adjacent to zinc finger domain 1B	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
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GO Annotations	Cellular Component	Condensed Chromosome Nucleoplasm Pericentric Heterochromatin Nuclear Body Nuclear Replication Fork	Condensed Chromosome Fibrillar Center Nucleus Nucleoplasm Chromatin Silencing Complex Cytosol NURF Complex RSF Complex Intracellular Membrane-bounded Organelle Nuclear Replication Fork
	Molecular Function	Protein Tyrosine Kinase Activity Non-membrane Spanning Protein Tyrosine Kinase Activity Protein Binding ATP Binding Zinc Ion Binding Histone Kinase Activity Histone Binding	DNA Binding Helicase Activity Protein Binding ATP Binding DNA-dependent ATPase Activity ATPase Activity Nucleosome Binding Histone Binding
	Biological Process	Chromatin Assembly Or Disassembly Chromatin Remodeling Regulation Of Transcription By RNA Polymerase II Cellular Response To DNA Damage Stimulus Histone Phosphorylation Peptidyl-tyrosine Phosphorylation Positive Regulation Of Gene Expression, Epigenetic	RDNA Heterochromatin Assembly Nucleosome Assembly Chromatin Remodeling DNA-templated Transcription, Initiation Regulation Of Transcription By RNA Polymerase II Nucleosome Positioning CENP-A Containing Nucleosome Assembly ATP-dependent Chromatin Remodeling Positive Regulation Of Gene Expression, Epigenetic Positive Regulation Of Transcription By RNA Polymerase II Cellular Response To Leukemia Inhibitory Factor
Pathways		B-WICH complex positively regulates rRNA expression Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks	NoRC negatively regulates rRNA expression B-WICH complex positively regulates rRNA expression Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks Deposition of new CENPA-containing nucleosomes at the centromere
Drugs			Beta-D-Glucose 4-Deoxy-Alpha-D-Glucose
Diseases
GWAS		C-reactive protein levels or HDL-cholesterol levels (pleiotropy) ( 27286809) Hypertriglyceridemia ( 23505323) Hyperuricemia ( 29124443) Lamb consumption ( 32066663) Malaria ( 31844061) Meat-related diet ( 32066663) Metabolic syndrome ( 31589552) Migraine ( 27182965) Non-oily fish consumption ( 32066663) Platelet count ( 32888494) Protein C levels ( 20802025) Pursuit maintenance gain ( 29064472) Serum uric acid levels ( 30993211) Triglyceride levels ( 32203549) Triglycerides ( 20864672) Urate levels ( 31985003 23263486) Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction) ( 28448500) Waist-to-hip ratio adjusted for body mass index ( 28448500)	Height ( 31562340) Malaria ( 31844061)
Interacting Genes		10 interacting genes: CDT1 MTNR1A MYO1C NR4A2 PCNA SMARCA1 SMARCA5 SMARCC2 SMARCE1 SUMO2	18 interacting genes: BAZ1A BAZ1B BAZ2A CDT1 CHRAC1 CREB1 CTNNB1 DNMT3B H3-3A H3C1 H4-16 HDAC2 MAF POLE3 PTEN RAD21 RSF1 SATB1
Entrez ID		9031	8467
HPRD ID		10416	04538
Ensembl ID		ENSG00000009954	ENSG00000153147
Uniprot IDs		Q9UIG0	O60264
PDB IDs		1F62 5NNF	6NE3
Enriched GO Terms of Interacting Partners?
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