BAZ1B and MYO1C

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology)
HPRD (in vivo)

		BAZ1B	MYO1C
Description		bromodomain adjacent to zinc finger domain 1B	myosin IC
Image
GO Annotations	Cellular Component	Condensed Chromosome Nucleoplasm Pericentric Heterochromatin Nuclear Body Nuclear Replication Fork	Stress Fiber Nuclear Pore Nucleoplasm Nucleolus Cytoplasm Cytosol Plasma Membrane Microvillus Brush Border Basal Plasma Membrane Actin Cytoskeleton Membrane Lateral Plasma Membrane Unconventional Myosin Complex Nuclear Body Cytoplasmic Vesicle Membrane Filamentous Actin Vesicle Ruffle Membrane Membrane Raft Phagocytic Vesicle Stereocilium Membrane Extracellular Exosome
	Molecular Function	Protein Tyrosine Kinase Activity Non-membrane Spanning Protein Tyrosine Kinase Activity Protein Binding ATP Binding Zinc Ion Binding Histone Kinase Activity Histone Binding	Microfilament Motor Activity Signaling Receptor Binding Protein Binding Calmodulin Binding ATP Binding Protein C-terminus Binding Actin-dependent ATPase Activity Small GTPase Binding Actin Filament Binding
	Biological Process	Chromatin Assembly Or Disassembly Chromatin Remodeling Regulation Of Transcription By RNA Polymerase II Cellular Response To DNA Damage Stimulus Histone Phosphorylation Peptidyl-tyrosine Phosphorylation Positive Regulation Of Gene Expression, Epigenetic	Protein Targeting Protein Targeting To Membrane Actin Filament Organization Vesicle Transport Along Actin Filament Positive Regulation Of Cell Migration Positive Regulation Of Actin Filament Polymerization Positive Regulation Of Cell Migration By Vascular Endothelial Growth Factor Signaling Pathway Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Positive Regulation Of Gene Expression, Epigenetic MRNA Transport Cellular Response To Interferon-gamma Positive Regulation Of Protein Targeting To Membrane Positive Regulation Of Cellular Response To Insulin Stimulus Positive Regulation Of Vascular Endothelial Growth Factor Signaling Pathway Regulation Of Bicellular Tight Junction Assembly
Pathways		B-WICH complex positively regulates rRNA expression Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks	Translocation of SLC2A4 (GLUT4) to the plasma membrane Regulation of actin dynamics for phagocytic cup formation FCGR3A-mediated phagocytosis
Drugs
Diseases
GWAS		C-reactive protein levels or HDL-cholesterol levels (pleiotropy) ( 27286809) Hypertriglyceridemia ( 23505323) Hyperuricemia ( 29124443) Lamb consumption ( 32066663) Malaria ( 31844061) Meat-related diet ( 32066663) Metabolic syndrome ( 31589552) Migraine ( 27182965) Non-oily fish consumption ( 32066663) Platelet count ( 32888494) Protein C levels ( 20802025) Pursuit maintenance gain ( 29064472) Serum uric acid levels ( 30993211) Triglyceride levels ( 32203549) Triglycerides ( 20864672) Urate levels ( 31985003 23263486) Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction) ( 28448500) Waist-to-hip ratio adjusted for body mass index ( 28448500)	Appendicular lean mass ( 33097823) Atrial fibrillation ( 30061737) Mean platelet volume ( 32888494) Neutrophil count ( 32888494) Pulse pressure ( 30578418) White blood cell count ( 32888494)
Interacting Genes		10 interacting genes: CDT1 MTNR1A MYO1C NR4A2 PCNA SMARCA1 SMARCA5 SMARCC2 SMARCE1 SUMO2	6 interacting genes: BAZ1B CBL CDC42 KHDRBS1 PTEN RRN3
Entrez ID		9031	4641
HPRD ID		10416	09411
Ensembl ID		ENSG00000009954	ENSG00000197879
Uniprot IDs		Q9UIG0	O00159
PDB IDs		1F62 5NNF	4BYF
Enriched GO Terms of Interacting Partners?
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