TAF1B and TAF1A

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology, pull down)
HPRD (in vitro)

		TAF1B	TAF1A
Description		TATA-box binding protein associated factor, RNA polymerase I subunit B	TATA-box binding protein associated factor, RNA polymerase I subunit A
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm RNA Polymerase Transcription Factor SL1 Complex Nucleolus RNA Polymerase I Core Factor Complex	RNA Polymerase I Transcription Regulator Complex Nucleoplasm Microtubule Cytoskeleton
	Molecular Function	RNA Polymerase I Core Promoter Sequence-specific DNA Binding Protein Binding TBP-class Protein Binding Metal Ion Binding	DNA Binding Protein Binding
	Biological Process	RNA Polymerase I Preinitiation Complex Assembly Transcription, DNA-templated Transcription Initiation From RNA Polymerase I Promoter Transcription Elongation From RNA Polymerase I Promoter Termination Of RNA Polymerase I Transcription Nucleolar Large RRNA Transcription By RNA Polymerase I Positive Regulation Of Gene Expression, Epigenetic	Transcription By RNA Polymerase I Transcription Initiation From RNA Polymerase I Promoter Transcription Elongation From RNA Polymerase I Promoter Termination Of RNA Polymerase I Transcription Transcription By RNA Polymerase II Positive Regulation Of Gene Expression, Epigenetic
Pathways		SIRT1 negatively regulates rRNA expression NoRC negatively regulates rRNA expression B-WICH complex positively regulates rRNA expression RNA Polymerase I Transcription Initiation RNA Polymerase I Transcription Initiation RNA Polymerase I Promoter Escape RNA Polymerase I Transcription Termination	SIRT1 negatively regulates rRNA expression NoRC negatively regulates rRNA expression B-WICH complex positively regulates rRNA expression RNA Polymerase I Transcription Initiation RNA Polymerase I Transcription Initiation RNA Polymerase I Promoter Escape RNA Polymerase I Transcription Termination
Drugs
Diseases
GWAS		Dental caries (decayed, missing and filled teeth) ( 31533690) Dental caries (decayed, missing and filled tooth surfaces) ( 31533690) Egg allergy (maternal genetic effects) ( 29489655) Non-response to selective serotonin reuptake inhibitors and depression ( 27622933) Nonsyndromic cleft lip with cleft palate ( 28232668) Prostate cancer ( 23535732)	Trunk fat mass ( 28552196)
Interacting Genes		27 interacting genes: ACADVL APP CALR EP300 ESR1 H2AC20 H2BC21 H3C1 H4C1 MEOX2 MYC NAPB NEDD4 NEDD4L PGR RRN3 RXRA SRPK1 TAF1A TAF1C TAF1D TBP THAP7 TP53 TRB TRIM24 UBTF	20 interacting genes: ANP32A ESR1 H2AC20 H2BC21 H3-4 H3C1 H4-16 H4C1 JMJD6 NKAPD1 POLR1G RRN3 RUNX2 SET TAF12 TAF1B TAF1C TBP TP53 UBTF
Entrez ID		9014	9015
HPRD ID		05363	05362
Ensembl ID		ENSG00000115750	ENSG00000143498
Uniprot IDs		Q53T94	A8K4K5 B4DS21 Q15573
PDB IDs
Enriched GO Terms of Interacting Partners?
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