TSR2 and CMIP

Data Source:
BioGRID (two hybrid)

		TSR2	CMIP
Description		TSR2 ribosome maturation factor	c-Maf inducing protein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Nucleoplasm Cytosol
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Maturation Of SSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA)	In Utero Embryonic Development
Pathways
Drugs
Diseases
GWAS		Prostate cancer ( 31562322)	Adiponectin levels ( 22479202 31178129 24105470) Adult body size ( 32376654) Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin) ( 23648065) Age-related cataracts ( 25352737) Apolipoprotein A1 levels ( 32203549) Apolipoprotein B levels ( 32203549) Body size at age 10 ( 32376654) Cadmium levels ( 26025379) Dehydroepiandrosterone sulphate levels ( 28887542) Diastolic blood pressure ( 28135244 27841878) Eosinophil counts ( 32888494) Eosinophil percentage of white cells ( 32888494) HDL cholesterol ( 24097068 30275531 25961943 20686565) HDL cholesterol levels ( 32203549 28334899 30698716) HDL cholesterol levels in current drinkers ( 30698716) HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) HDL cholesterol levels x short total sleep time interaction (2df test) ( 31719535) Heel bone mineral density ( 30598549 28869591) Height ( 31562340) Hematology traits ( 30576415) High density lipoprotein cholesterol levels ( 29403010) Lymphocyte percentage of white cells ( 32888494) Mean spheric corpuscular volume ( 32888494) Medication use (agents acting on the renin-angiotensin system) ( 31015401) Medication use (beta blocking agents) ( 31015401) Medication use (calcium channel blockers) ( 31015401) Medication use (diuretics) ( 31015401) Menarche (age at onset) ( 23667675) Metabolic syndrome ( 31589552) Neuritic plaque ( 31497858) Neutrophil count ( 32888494) Neutrophil percentage of white cells ( 32888494) Pursuit maintenance gain ( 29064472) Systolic blood pressure ( 27841878) Triglyceride levels ( 32203549 32154731 30698716) Triglyceride levels in current drinkers ( 30698716) Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Triglycerides ( 30275531) Type 2 diabetes ( 28566273 30054458 30297969 32499647 22158537 28869590) Urate levels ( 31578528) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction) ( 28448500) Waist-to-hip ratio adjusted for BMI x sex interaction ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971) Waist-to-hip ratio adjusted for body mass index ( 25673412 28448500) White blood cell count ( 32888494)
Interacting Genes		24 interacting genes: CAMK2A CMIP CREB5 DAPL1 DISC1 EXOSC3 GABARAP GABARAPL2 GAS2L3 GSC2 KIF16B KIFC3 LAMB2 MAP1LC3C MEOX2 PIAS2 PRKAB2 PTRHD1 RBM48 RPS26 SPATC1L ZBTB9 ZNF474 ZNF620	5 interacting genes: FLNA MTNR1A TRIM54 TSR2 ZC4H2
Entrez ID		90121	80790
HPRD ID		06493	10839
Ensembl ID		ENSG00000158526	ENSG00000153815
Uniprot IDs		A0A024R9U9 Q969E8	A0A087WU05 Q8IY22
PDB IDs
Enriched GO Terms of Interacting Partners?
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