TSR2 and LAMB2

Data Source:
BioGRID (two hybrid)

		TSR2	LAMB2
Description		TSR2 ribosome maturation factor	laminin subunit beta 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Extracellular Region Basement Membrane Laminin-3 Complex Endoplasmic Reticulum Lumen Neuromuscular Junction Synaptic Cleft Laminin Complex Laminin-11 Complex Collagen-containing Extracellular Matrix Extracellular Exosome
	Molecular Function	Protein Binding	Integrin Binding Structural Molecule Activity Extracellular Matrix Structural Constituent Protein Binding
	Biological Process	Maturation Of SSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA)	Axon Guidance Neuromuscular Junction Development Visual Perception Animal Organ Morphogenesis Tissue Development Astrocyte Development Schwann Cell Development Cell Migration Extracellular Matrix Organization Substrate Adhesion-dependent Cell Spreading Post-translational Protein Modification Cellular Protein Metabolic Process Axon Extension Involved In Regeneration Retina Development In Camera-type Eye Basement Membrane Assembly Metanephric Glomerular Visceral Epithelial Cell Development Metanephric Glomerular Basement Membrane Development
Pathways			Laminin interactions Laminin interactions Non-integrin membrane-ECM interactions ECM proteoglycans Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) MET activates PTK2 signaling Post-translational protein phosphorylation
Drugs
Diseases			Pierson syndrome
GWAS		Prostate cancer ( 31562322)	Blood protein levels ( 28240269) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Mood instability ( 31168069) PR interval ( 32439900) Resting heart rate ( 27798624) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Ulcerative colitis ( 28067908)
Interacting Genes		24 interacting genes: CAMK2A CMIP CREB5 DAPL1 DISC1 EXOSC3 GABARAP GABARAPL2 GAS2L3 GSC2 KIF16B KIFC3 LAMB2 MAP1LC3C MEOX2 PIAS2 PRKAB2 PTRHD1 RBM48 RPS26 SPATC1L ZBTB9 ZNF474 ZNF620	9 interacting genes: ATXN7 KPNA2 ORC5 PIK3R2 PLEKHA5 RBL1 STAT3 TSR2 ZNF512B
Entrez ID		90121	3913
HPRD ID		06493	01034
Ensembl ID		ENSG00000158526	ENSG00000172037
Uniprot IDs		A0A024R9U9 Q969E8	P55268
PDB IDs
Enriched GO Terms of Interacting Partners?
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