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LHX4 and CDK3
Data Source:
BioGRID
(two hybrid)
LHX4
CDK3
Description
LIM homeobox 4
cyclin dependent kinase 3
Image
GO Annotations
Cellular Component
Chromatin
Nucleus
Nucleus
Molecular Function
RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
Protein Binding
Methyl-CpG Binding
Sequence-specific DNA Binding
Metal Ion Binding
Sequence-specific Double-stranded DNA Binding
Cyclin-dependent Protein Serine/threonine Kinase Activity
Protein Binding
ATP Binding
Biological Process
Placenta Development
Regulation Of Transcription By RNA Polymerase II
Motor Neuron Axon Guidance
Animal Organ Morphogenesis
Medial Motor Column Neuron Differentiation
Neuron Differentiation
Negative Regulation Of Apoptotic Process
Positive Regulation Of Transcription By RNA Polymerase II
G1/S Transition Of Mitotic Cell Cycle
Protein Phosphorylation
Cellular Response To DNA Damage Stimulus
Cell Population Proliferation
G0 To G1 Transition
Cell Division
Regulation Of Cell Cycle
Pathways
Regulation of expression of SLITs and ROBOs
Drugs
Diseases
Pituitary Dwarfism (PD); Isolated growth hormone deficiency (IGHD); Short Stature and Pituitary Defects (SSPD); Insulin-like growth factor 1 deficiency (IGFD)
GWAS
Refractive error (
32231278
)
Interacting Genes
53 interacting genes:
ADAMTSL4
ARL2
AXIN1
BANP
BOD1L2
CDK3
CENPS-CORT
CHCHD2
CORO1B
DCAF10
DHRS1
DNAJB13
ERO1A
FDX2
GOLGA2
HOXC5
IFT172
IKZF1
INO80B
KLHL38
KRT38
KRT40
LDB1
LDB2
LONRF1
MAPRE3
MRS2
MYOZ1
NRF1
ORC6
PARP11
POU1F1
QRICH1
SCAND1
SH2D1A
SNRNP25
SNRPA
SSX1
TCAP
TCF4
TP53BP2
TRAPPC6A
TRMT11
TSEN54
TSTD2
TXNDC5
UBQLN1
USP2
WASHC3
YY1
ZBTB2
ZNF354C
ZNF76
39 interacting genes:
APP
CABLES1
CABLES2
CCNA2
CCNC
CCND3
CCNE1
CCNE2
CCNH
CCNI
CDC37
CDKN1A
CDKN1B
CDKN3
CKS1B
CKS2
E2F1
E2F2
E2F3
FOXP2
FRS2
KIR3DL1
LHX3
LHX4
MEOX2
NEDD4L
NELFA
OR2G6
OTX2
PAX5
PAX6
PAX8
PPARA
RACGAP1
RB1
SPDYE4
STN1
TRIM55
TRIM63
Entrez ID
89884
1018
HPRD ID
03686
00446
Ensembl ID
ENSG00000121454
ENSG00000250506
Uniprot IDs
A0A0S2Z5S4
Q969G2
Q00526
PDB IDs
5HOD
1LFN
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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