KCNK17 and BBS2

Data Source:
BioGRID (proximity labelling technology)

		KCNK17	BBS2
Description		potassium two pore domain channel subfamily K member 17	Bardet-Biedl syndrome 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane	Cytosol Microvillus Membrane Motile Cilium Stereocilium BBSome Ciliary Basal Body Neuron Projection Ciliary Membrane
	Molecular Function	Voltage-gated Ion Channel Activity Potassium Channel Activity Potassium Ion Leak Channel Activity	RNA Polymerase II Repressing Transcription Factor Binding Protein Binding
	Biological Process	Potassium Ion Transport Stabilization Of Membrane Potential Regulation Of Ion Transmembrane Transport Potassium Ion Transmembrane Transport	Sperm Axoneme Assembly Visual Perception Protein Localization Negative Regulation Of Gene Expression Artery Smooth Muscle Contraction Striatum Development Hippocampus Development Cerebral Cortex Development Adult Behavior Melanosome Transport Protein Localization To Organelle Negative Regulation Of Appetite By Leptin-mediated Signaling Pathway Negative Regulation Of Multicellular Organism Growth Positive Regulation Of Multicellular Organism Growth Vasodilation Golgi To Plasma Membrane Protein Transport Fat Cell Differentiation Photoreceptor Cell Maintenance Brain Morphogenesis Cartilage Development Cilium Assembly Regulation Of Cilium Beat Frequency Involved In Ciliary Motility Non-motile Cilium Assembly
Pathways		TWIK-related alkaline pH activated K+ channel (TALK) Phase 4 - resting membrane potential	BBSome-mediated cargo-targeting to cilium
Drugs
Diseases			Bardet-Biedl syndrome (BBS)
GWAS		Apolipoprotein B levels ( 32203549) Cholesterol, total ( 24097068)
Interacting Genes		1 interacting genes: VKORC1	15 interacting genes: BHMT EEF1A1 EPAS1 EXOC7 FHOD1 FNDC3B HNRNPF HSCB KRT18 LMO4 MDFI NRF1 PAX2 PSME3 RBPMS
Entrez ID		89822	583
HPRD ID		09566	05855
Ensembl ID		ENSG00000124780	ENSG00000125124
Uniprot IDs		Q96T54	Q9BXC9
PDB IDs
Enriched GO Terms of Interacting Partners?
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