P4HA2 and PRRC2A

Data Source:
HPRD (two hybrid)

		P4HA2	PRRC2A
Description		prolyl 4-hydroxylase subunit alpha 2	proline rich coiled-coil 2A
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Endoplasmic Reticulum Endoplasmic Reticulum Lumen Cytosol Intracellular Membrane-bounded Organelle	Nucleoplasm Cytosol Plasma Membrane Membrane Extracellular Exosome
	Molecular Function	Procollagen-proline 4-dioxygenase Activity Iron Ion Binding Electron Transfer Activity Oxidoreductase Activity, Acting On Single Donors With Incorporation Of Molecular Oxygen, Incorporation Of Two Atoms Of Oxygen L-ascorbic Acid Binding	RNA Binding Protein Binding
	Biological Process	Peptidyl-proline Hydroxylation To 4-hydroxy-L-proline Electron Transport Chain	Cell Differentiation
Pathways		Collagen biosynthesis and modifying enzymes
Drugs		Proline
Diseases
GWAS		Asthma ( 31619474) Asthma or allergic disease (pleiotropy) ( 29785011) Blood protein levels ( 29875488) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Crohn's disease ( 28067908 22412388) Giant cell arteritis ( 28041642) Height ( 28552196) Inflammatory bowel disease ( 28067908) Intracranial aneurysm ( 33199917) Intraocular pressure ( 29617998) Subcortical volume (MOSTest) ( 32665545) Sum eosinophil basophil counts ( 27863252) Ulcerative colitis ( 28067908) Youthful appearance (self-reported) ( 32339537)	Adult body size ( 32376654) Asthma ( 31619474) Asthma (childhood onset) ( 31619474) Asthma and major depressive disorder ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Blood metabolite ratios ( 24816252) Blood protein levels ( 28240269) Childhood body mass index ( 33045005) Hand grip strength ( 29691431) Height ( 28552196) Hemoglobin levels ( 32327693) Inflammatory bowel disease ( 28067908) Leukocyte telomere length ( 32109421) Malaria ( 31844061) Menopause (age at onset) ( 22267201) Metabolite levels ( 31628463) Platelet distribution width ( 32888494) Schizophrenia ( 23894747) Systolic blood pressure ( 30578418) Ulcerative colitis ( 28067908) Waist circumference ( 31928498)
Interacting Genes		6 interacting genes: CLNK CREB3 FHL3 P4HB PRRC2A TNS4	28 interacting genes: ATN1 ATXN1 C1QBP CCR10 CPSF1 DDX20 EIF3E EWSR1 FGA GANAB GORASP2 GRB2 HNRNPA1 HNRNPM IFT88 IMMT JUN MAD2L2 MAN2C1 P4HA2 PRMT2 PSMA3 QARS1 RBFOX1 RERE SRPK2 SSR3 UBAP2L
Entrez ID		8974	7916
HPRD ID		11862	00807
Ensembl ID		ENSG00000072682	ENSG00000204469
Uniprot IDs		O15460 Q05DA4	A0A1U9X974 P48634
PDB IDs		6EVL 6EVM 6EVN 6EVO 6EVP
Enriched GO Terms of Interacting Partners?
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