P4HA2

Description		prolyl 4-hydroxylase subunit alpha 2
Image
GO Annotations	Cellular Component	Nucleoplasm Endoplasmic Reticulum Endoplasmic Reticulum Lumen Cytosol Intracellular Membrane-bounded Organelle
	Molecular Function	Procollagen-proline 4-dioxygenase Activity Iron Ion Binding Electron Transfer Activity Oxidoreductase Activity, Acting On Single Donors With Incorporation Of Molecular Oxygen, Incorporation Of Two Atoms Of Oxygen L-ascorbic Acid Binding
	Biological Process	Peptidyl-proline Hydroxylation To 4-hydroxy-L-proline Electron Transport Chain
Pathways		Collagen biosynthesis and modifying enzymes
Drugs		Proline
Diseases
GWAS		Asthma ( 31619474) Asthma or allergic disease (pleiotropy) ( 29785011) Blood protein levels ( 29875488) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Crohn's disease ( 28067908 22412388) Giant cell arteritis ( 28041642) Height ( 28552196) Inflammatory bowel disease ( 28067908) Intracranial aneurysm ( 33199917) Intraocular pressure ( 29617998) Subcortical volume (MOSTest) ( 32665545) Sum eosinophil basophil counts ( 27863252) Ulcerative colitis ( 28067908) Youthful appearance (self-reported) ( 32339537)
Novel Interacting Genes		2 novel interacting genes: CD86 PRKAR2A
Interacting Genes		6 interacting genes: CLNK CREB3 FHL3 P4HB PRRC2A TNS4
Entrez ID		8974
HPRD ID		11862
Ensembl ID		ENSG00000072682
Uniprot IDs		O15460 Q05DA4
PDB IDs		6EVL 6EVM 6EVN 6EVO 6EVP
Enriched GO Terms of Interacting Partners?
Tagcloud ?