NAE1 and NEDD8

  • Data Source:
  • BioGRID (x-ray crystallography, affinity chromatography technology)
  • HPRD (in vivo)

NAE1

NEDD8

Description NEDD8 activating enzyme E1 subunit 1 NEDD8 ubiquitin like modifier
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Mean corpuscular volume ( 29403010)
  • Systolic blood pressure (cigarette smoking interaction) ( 26752167)
Interacting Genes 10 interacting genes: ALG8 APP GARS1 NEDD8 SREBF2 TP53BP2 TRIP12 UBA3 UBE2F UBQLN4 42 interacting genes: AHR ARIH2 ATXN3 CBLB CDC34 COPS5 COPS6 CTRC CUL1 CUL2 CUL3 CUL4B DNMT3B GARS1 GHR HGS HIF1A HSPA4 N4BP1 NAE1 NUB1 OTUB1 OTUD5 PARP1 POLI PSMA6 PSMD4 PTK2 RAD23A SENP8 SMURF1 TP53 UBA2 UBA3 UBE2K UBE2M UBL7 UBQLN1 UBXN7 UCHL1 UCHL3 YAF2
Entrez ID 8883 4738
HPRD ID 04545 04412
Ensembl ID ENSG00000159593 ENSG00000129559
Uniprot IDs Q13564 Q15843
PDB IDs 1R4M 1R4N 1TT5 1YOV 2NVU 3DBH 3DBL 3DBR 3GZN 1NDD 1R4M 1R4N 1XT9 2BKR 2KO3 2N7K 2NVU 3DBH 3DBL 3DBR 3DQV 3GZN 4F8C 4FBJ 4HCP 4P5O 6R7F 6R7I 6TTU
Enriched GO Terms of Interacting Partners?
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