KRTAP8-1 and TBX18

Data Source:
BioGRID (two hybrid)

		KRTAP8-1	TBX18
Description		keratin associated protein 8-1	T-box transcription factor 18
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Intermediate Filament	Chromatin Nucleus Nucleoplasm RNA Polymerase II Transcription Repressor Complex
	Molecular Function	Protein Binding	Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Protein Binding Protein Homodimerization Activity Sequence-specific Double-stranded DNA Binding
	Biological Process	Keratinization	Negative Regulation Of Transcription By RNA Polymerase II Cell Fate Specification Somitogenesis Sinoatrial Node Development Regulation Of Transcription By RNA Polymerase II Morphogenesis Of Embryonic Epithelium Smooth Muscle Cell Differentiation Negative Regulation Of Canonical Wnt Signaling Pathway Involved In Neural Plate Anterior/posterior Pattern Formation Sinoatrial Node Cell Fate Commitment Sinoatrial Node Cell Development Ureter Development Cochlea Morphogenesis Regulation Of SA Node Cell Action Potential
Pathways		Keratinization
Drugs
Diseases
GWAS		Gut microbiota (bacterial taxa) ( 27723756) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223)	Diabetic retinopathy in type 2 diabetes ( 25364816) Lung function ( 31902109) Monobrow ( 27182965) Pulse pressure ( 30224653)
Interacting Genes		78 interacting genes: AANAT AGXT AOC1 ARID5A ATG9A ATXN1L BANP BCAS2 BHLHE40 C11orf16 C1orf94 C20orf85 CAMK2A CCDC17 CCNK CDA CERCAM CREB5 CRYAB CYSRT1 DAB1 DAZAP2 DMRTB1 DTX2 FAAP20 FAM168A FAM83A FOXD2 FOXP3 GATA2 GCM2 GLIS2 HEY2 HOXC8 HYPK KRTAP12-4 KRTAP19-5 KRTAP26-1 MFSD13A MKRN3 MYOZ3 NKX2-5 NOXA1 P4HA3 PAX3 PITX1 PLSCR4 POGZ POU6F2 PPP1R32 PROP1 PRR13 PRR35 PSMA3 RAMAC RBPMS RBPMS2 RNF38 RUSC1 SMR3A SMUG1 SNRPC TBX18 TEKT3 TIAL1 TLE5 TLX3 TMSB4X TNIP1 TNPO2 TSPYL6 VENTX VEZF1 YTHDF1 ZBTB32 ZC3H10 ZIC1 ZNF34	4 interacting genes: ARC KRTAP8-1 PLEKHG4 TRAF1
Entrez ID		337879	9096
HPRD ID		11221	19076
Ensembl ID		ENSG00000183640	ENSG00000112837
Uniprot IDs		Q8IUC2	O95935
PDB IDs
Enriched GO Terms of Interacting Partners?
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