SUCLG2 and SUCLG1

Data Source:
HPRD (in vitro)

		SUCLG2	SUCLG1
Description		succinate-CoA ligase GDP-forming subunit beta	succinate-CoA ligase GDP/ADP-forming subunit alpha
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GO Annotations	Cellular Component	Mitochondrion Mitochondrial Matrix Plasma Membrane Succinate-CoA Ligase Complex Succinate-CoA Ligase Complex (GDP-forming)	Mitochondrion Mitochondrial Matrix Succinate-CoA Ligase Complex (ADP-forming)
	Molecular Function	Magnesium Ion Binding Succinate-CoA Ligase (ADP-forming) Activity Succinate-CoA Ligase (GDP-forming) Activity Protein Binding ATP Binding GTP Binding GDP Binding Protein-containing Complex Binding	Nucleotide Binding RNA Binding Succinate-CoA Ligase (ADP-forming) Activity Succinate-CoA Ligase (GDP-forming) Activity Protein Binding
	Biological Process	Tricarboxylic Acid Cycle Succinyl-CoA Metabolic Process Succinate Metabolic Process	Tricarboxylic Acid Cycle
Pathways		Citric acid cycle (TCA cycle)	Citric acid cycle (TCA cycle)
Drugs		Phenethyl Isothiocyanate
Diseases			Mitochondrial DNA depletion syndrome (MDS)
GWAS		Blood metabolite levels ( 24816252) Body mass index ( 28552196) Cerebrospinal AB1-42 levels in Alzheimer's disease dementia ( 25027320) Corneal astigmatism ( 22144915) Diabetic kidney disease ( 26305897) FEV1 ( 30804560) Height ( 20881960) Hip circumference ( 28552196) IgE levels ( 23146381) Lung function (FVC) ( 28166213 30804560) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Metabolite levels ( 23823483) Spontaneous preterm birth with premature rupture of membranes ( 31194736) Thrombin-activatable fibrinolysis inhibitor activation peptide ( 29378355) Urinary metabolite levels in chronic kidney disease ( 31959995)	Coronary artery calcification ( 23870195) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Gut microbiota (functional units) ( 27694959)
Interacting Genes		3 interacting genes: GPR143 SGCG SUCLG1	2 interacting genes: CHMP1B SUCLG2
Entrez ID		8801	8802
HPRD ID		06799	18128
Ensembl ID		ENSG00000172340	ENSG00000163541
Uniprot IDs		Q96I99	P53597
PDB IDs		6WCV	6G4Q 6WCV
Enriched GO Terms of Interacting Partners?
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