SUCLG2 and SGCG

Data Source:
BioGRID (two hybrid)

		SUCLG2	SGCG
Description		succinate-CoA ligase GDP-forming subunit beta	sarcoglycan gamma
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Matrix Plasma Membrane Succinate-CoA Ligase Complex Succinate-CoA Ligase Complex (GDP-forming)	Cytoplasm Cytoskeleton Plasma Membrane Sarcoglycan Complex Integral Component Of Membrane Sarcolemma
	Molecular Function	Magnesium Ion Binding Succinate-CoA Ligase (ADP-forming) Activity Succinate-CoA Ligase (GDP-forming) Activity Protein Binding ATP Binding GTP Binding GDP Binding Protein-containing Complex Binding	Protein Binding
	Biological Process	Tricarboxylic Acid Cycle Succinyl-CoA Metabolic Process Succinate Metabolic Process	Muscle Organ Development Cardiac Muscle Tissue Development Heart Contraction
Pathways		Citric acid cycle (TCA cycle)
Drugs		Phenethyl Isothiocyanate
Diseases			Sarcoglycanopathies, including: Limb-girdle muscular dystrophy (LGMD) 2C; Limb-girdle muscular dystrophy (LGMD) 2D; Limb-girdle muscular dystrophy (LGMD) 2E; Limb-girdle muscular dystrophy (LGMD) 2F Limb-girdle muscular dystrophy (LGMD)
GWAS		Blood metabolite levels ( 24816252) Body mass index ( 28552196) Cerebrospinal AB1-42 levels in Alzheimer's disease dementia ( 25027320) Corneal astigmatism ( 22144915) Diabetic kidney disease ( 26305897) FEV1 ( 30804560) Height ( 20881960) Hip circumference ( 28552196) IgE levels ( 23146381) Lung function (FVC) ( 28166213 30804560) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Metabolite levels ( 23823483) Spontaneous preterm birth with premature rupture of membranes ( 31194736) Thrombin-activatable fibrinolysis inhibitor activation peptide ( 29378355) Urinary metabolite levels in chronic kidney disease ( 31959995)	Alanine aminotransferase levels ( 31219225) Asthma ( 27611488) Atrial fibrillation ( 30061737) Bipolar disorder ( 21738484) Central corneal thickness ( 29760442) Corneal structure ( 23291589) Number of alcoholic drinks required to feel an effect (first five times drinking) ( 31270906) Type 2 diabetes ( 23300278)
Interacting Genes		3 interacting genes: GPR143 SGCG SUCLG1	20 interacting genes: APP CCT6A CLDN5 DNAJB6 DYSF ENO1 ENO3 FLNC HSPA1B MYBPC1 MYBPC2 MYLPF PSAP PYGM SGCB SGCD SPACA1 SSPN SUCLG2 TTN
Entrez ID		8801	6445
HPRD ID		06799	07039
Ensembl ID		ENSG00000172340	ENSG00000102683
Uniprot IDs		Q96I99	Q13326
PDB IDs		6WCV
Enriched GO Terms of Interacting Partners?
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