CBR1 and CHAF1B

Data Source:
BioGRID (biochemical)

		CBR1	CHAF1B
Description		carbonyl reductase 1	chromatin assembly factor 1 subunit B
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol Extracellular Exosome Extracellular Vesicle	Chromatin Nucleus Nucleoplasm Cytoplasm Cytosol Protein-containing Complex CAF-1 Complex
	Molecular Function	Carbonyl Reductase (NADPH) Activity Oxidoreductase Activity, Acting On NAD(P)H, Quinone Or Similar Compound As Acceptor 15-hydroxyprostaglandin-D Dehydrogenase (NADP+) Activity 15-hydroxyprostaglandin Dehydrogenase (NADP+) Activity Prostaglandin-E2 9-reductase Activity	Chromatin Binding Protein Binding Histone Binding Unfolded Protein Binding
	Biological Process	Drug Metabolic Process Cyclooxygenase Pathway Epithelial Cell Differentiation Vitamin K Metabolic Process	DNA Replication DNA Repair Nucleosome Assembly DNA Replication-dependent Nucleosome Assembly Cell Cycle Chromatin Assembly
Pathways		Synthesis of Prostaglandins (PG) and Thromboxanes (TX)
Drugs		Rutin Resveratrol Heptaethylene glycol 2-(2-{2-[2-(2-{2-[2-(2-Ethoxy-Ethoxy)-Ethoxy]-Ethoxy}-Ethoxy)-Ethoxy]-Ethoxy}-Ethoxy)-Ethanol, Polyethyleneglycol Peg400 Quercetin 3-(4-Amino-1-Tert-Butyl-1h-Pyrazolo[3,4-D]Pyrimidin-3-Yl)Phenol Curcumin Curcumin sulfate
Diseases
GWAS		Blood protein levels ( 30072576 29875488) Metabolite levels ( 23823483) Mitral valve prolapse ( 26301497)	Creatinine levels ( 29403010) Height ( 31562340) Pulmonary function ( 23932459)
Interacting Genes		7 interacting genes: AGTR1 ERBB2 ERCC8 HTR2B PTPRF UBC VHL	10 interacting genes: APP ASF1A ASF1B CDK1 CDK2 CHAF1A H3-4 H3C6 RBBP4 SUMO2
Entrez ID		873	8208
HPRD ID		00267	03147
Ensembl ID		ENSG00000159228	ENSG00000159259
Uniprot IDs		A0A384NL53 P16152	Q13112
PDB IDs		1WMA 2PFG 3BHI 3BHJ 3BHM 4Z3D
Enriched GO Terms of Interacting Partners?
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