CBR1

Description		carbonyl reductase 1
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GO Annotations	Cellular Component	Cytosol Extracellular Exosome Extracellular Vesicle
	Molecular Function	Carbonyl Reductase (NADPH) Activity Oxidoreductase Activity, Acting On NAD(P)H, Quinone Or Similar Compound As Acceptor 15-hydroxyprostaglandin-D Dehydrogenase (NADP+) Activity 15-hydroxyprostaglandin Dehydrogenase (NADP+) Activity Prostaglandin-E2 9-reductase Activity
	Biological Process	Drug Metabolic Process Cyclooxygenase Pathway Epithelial Cell Differentiation Vitamin K Metabolic Process
Pathways		Synthesis of Prostaglandins (PG) and Thromboxanes (TX)
Drugs		Rutin Resveratrol Heptaethylene glycol 2-(2-{2-[2-(2-{2-[2-(2-Ethoxy-Ethoxy)-Ethoxy]-Ethoxy}-Ethoxy)-Ethoxy]-Ethoxy}-Ethoxy)-Ethanol, Polyethyleneglycol Peg400 Quercetin 3-(4-Amino-1-Tert-Butyl-1h-Pyrazolo[3,4-D]Pyrimidin-3-Yl)Phenol Curcumin Curcumin sulfate
Diseases
GWAS		Blood protein levels ( 30072576 29875488) Metabolite levels ( 23823483) Mitral valve prolapse ( 26301497)
Novel Interacting Genes		5 novel interacting genes: CHAF1B HRK JAK1 LZTS1 PRKAR2B
Interacting Genes		7 interacting genes: AGTR1 ERBB2 ERCC8 HTR2B PTPRF UBC VHL
Entrez ID		873
HPRD ID		00267
Ensembl ID		ENSG00000159228
Uniprot IDs		A0A384NL53 P16152
PDB IDs		1WMA 2PFG 3BHI 3BHJ 3BHM 4Z3D
Enriched GO Terms of Interacting Partners?
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