CHAF1B and ASF1A

Data Source:
HPRD (in vivo)

		CHAF1B	ASF1A
Description		chromatin assembly factor 1 subunit B	anti-silencing function 1A histone chaperone
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Cytoplasm Cytosol Protein-containing Complex CAF-1 Complex	Chromatin Nucleus Nucleoplasm Protein-containing Complex
	Molecular Function	Chromatin Binding Protein Binding Histone Binding Unfolded Protein Binding	Chromatin Binding Protein Binding Histone Binding
	Biological Process	DNA Replication DNA Repair Nucleosome Assembly DNA Replication-dependent Nucleosome Assembly Cell Cycle Chromatin Assembly	Osteoblast Differentiation DNA Repair Nucleosome Assembly DNA Replication-dependent Nucleosome Assembly DNA Replication-independent Nucleosome Assembly Negative Regulation Of Chromatin Silencing Muscle Cell Differentiation
Pathways			Formation of Senescence-Associated Heterochromatin Foci (SAHF)
Drugs
Diseases
GWAS		Creatinine levels ( 29403010) Height ( 31562340) Pulmonary function ( 23932459)	Mean platelet volume ( 32888494) Multiple sclerosis ( 31604244) QT interval ( 19305408)
Interacting Genes		10 interacting genes: APP ASF1A ASF1B CDK1 CDK2 CHAF1A H3-4 H3C6 RBBP4 SUMO2	35 interacting genes: ASF1B CDAN1 CHAF1A CHAF1B CHEK2 H3-3A H3-4 H3C3 H3C6 H4-16 H4C1 H4C11 H4C12 H4C13 H4C14 H4C15 H4C2 H4C3 H4C4 H4C5 H4C6 H4C8 H4C9 HIRA HTATIP2 MCM2 NASP PAFAH1B2 PRR3 ST13 TAF1 TLK1 TLK2 VPS28 ZDHHC17
Entrez ID		8208	25842
HPRD ID		03147	16459
Ensembl ID		ENSG00000159259	ENSG00000111875
Uniprot IDs		Q13112	Q9Y294
PDB IDs			1TEY 2I32 2IIJ 2IO5 3AAD 5C3I 6F0F 6F0G 6F0H
Enriched GO Terms of Interacting Partners?
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