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SNX3 and STX11
Data Source:
HPRD
(two hybrid)
SNX3
STX11
Description
sorting nexin 3
syntaxin 11
Image
No pdb structure
GO Annotations
Cellular Component
Cytoplasm
Early Endosome
Cytosol
Endosome Membrane
Clathrin-coated Vesicle
Retromer Complex
Early Endosome Membrane
Early Phagosome
Extracellular Exosome
Golgi Apparatus
Plasma Membrane
Synaptic Vesicle
Endomembrane System
Integral Component Of Membrane
SNARE Complex
Presynaptic Active Zone Membrane
Molecular Function
Protein Binding
Phosphatidylinositol-5-phosphate Binding
Protein Phosphatase Binding
Phosphatidylinositol-3-phosphate Binding
Phosphatidylinositol-4-phosphate Binding
Phosphatidylinositol-3,5-bisphosphate Binding
SNARE Binding
SNAP Receptor Activity
Protein Binding
Biological Process
Response To Bacterium
Membrane Invagination
Positive Regulation Of Neuron Projection Development
Protein Transport
Wnt Signaling Pathway
Protein Deubiquitination
Protein To Membrane Docking
Regulation Of Wnt Signaling Pathway
Endocytic Recycling
Late Endosome To Golgi Transport
Negative Regulation Of Protein Catabolic Process
Negative Regulation Of Viral Entry Into Host Cell
Negative Regulation Of Phagocytosis
Negative Regulation Of Protein Transport
Intralumenal Vesicle Formation
Negative Regulation Of Early Endosome To Late Endosome Transport
Intracellular Protein Transport
Exocytosis
Vesicle Fusion
Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane
Vesicle Docking
Membrane Fusion
Pathways
WNT ligand biogenesis and trafficking
Ub-specific processing proteases
Drugs
S,S-(2-Hydroxyethyl)Thiocysteine
Diseases
Familial hemophagocytic lymphohistiocytosis (FHPL), including the following three diseases: Perforin deficiency; Munc deficiency; STX11 deficiency
GWAS
Nicotine dependence symptom count (
25555482
)
Pre-treatment viral load in HIV-1 infection (
31219150
)
Interacting Genes
12 interacting genes:
ARL6IP1
BARD1
BRCA1
LIG4
PAXIP1
RAB7A
RPRM
SCNN1A
STX11
TSC22D2
USP10
VPS35
97 interacting genes:
APP
AXIN1
AXIN2
BLOC1S6
BYSL
C1orf109
CARD9
CCBE1
CCDC120
CCDC125
CCDC184
CCDC196
CCDC33
CCHCR1
CCNK
CDCA7L
CDR2L
CRYBA4
CTBP2
CWF19L2
DISC1
DUSP29
EIF1AD
EIF2B5
FAM110A
FAM161A
FAM161B
FAM74A4
FAM90A1
FARS2
GOLGA8EP
GOLGA8F
HAUS1
HGS
HOXA1
IKBKG
IKZF3
KAT5
KCTD9
KDM1A
KIFC3
KLC3
KRT75
KXD1
LENG1
LONRF1
MAGOHB
MBD3L1
MBIP
MEOX2
MFAP1
MID2
MIS18A
NDC80
NTAQ1
PKN1
PPP1R18
PRKAB2
PRPF18
PRPF31
PSMA3
PSMC3
RAD51D
RNF6
RNF8
RNPS1
RUNX1T1
SCNM1
SH2D4A
SHC3
SIKE1
SLC38A2
SMARCE1
SNAP23
SNAP25
SNX3
SOGA1
STX1A
STX4
SUV39H1
TADA3
TAF6L
TBK1
TCEA2
TCF4
TLE5
TNFRSF21
TRIM41
TSGA10IP
UBASH3A
USHBP1
VAMP2
VPS52
ZCCHC10
ZNF19
ZNF417
ZNF587
Entrez ID
8724
8676
HPRD ID
09333
09231
Ensembl ID
ENSG00000112335
ENSG00000135604
Uniprot IDs
O60493
O75558
PDB IDs
2MXC
2YPS
5F0J
5F0L
5F0M
5F0P
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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