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EDF1 and SOX4
Data Source:
BioGRID
(two hybrid)
EDF1
SOX4
Description
endothelial differentiation related factor 1
SRY-box transcription factor 4
Image
No pdb structure
GO Annotations
Cellular Component
Intracellular Anatomical Structure
Nucleus
Nucleoplasm
Nucleolus
Cytoplasm
Cytosol
Chromatin
Nucleus
Nucleoplasm
Transcription Regulator Complex
Cytoplasm
Mitochondrion
Molecular Function
TFIID-class Transcription Factor Complex Binding
DNA Binding
Transcription Coactivator Activity
RNA Binding
Protein Binding
Calmodulin Binding
Transcription Regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
DNA-binding Transcription Factor Activity
Protein Binding
MiRNA Binding
Sequence-specific Double-stranded DNA Binding
Biological Process
Regulation Of Transcription, DNA-templated
Multicellular Organism Development
Regulation Of Lipid Metabolic Process
Positive Regulation Of DNA Binding
Endothelial Cell Differentiation
Positive Regulation Of Transcription, DNA-templated
Skeletal System Development
Neural Tube Formation
Pro-B Cell Differentiation
Mitral Valve Morphogenesis
Cardiac Ventricle Formation
Cardiac Right Ventricle Morphogenesis
Atrial Septum Primum Morphogenesis
Noradrenergic Neuron Differentiation
Regulation Of Transcription, DNA-templated
DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest
Heart Development
Positive Regulation Of Cell Population Proliferation
Negative Regulation Of Cell Population Proliferation
Anatomical Structure Morphogenesis
Glial Cell Proliferation
Spinal Cord Development
Spinal Cord Motor Neuron Differentiation
Glial Cell Development
Cell Differentiation
T Cell Differentiation
Endocrine Pancreas Development
Negative Regulation Of Protein Ubiquitination
Regulation Of Protein Stability
Positive Regulation Of Insulin Secretion
Somatic Stem Cell Population Maintenance
Ascending Aorta Morphogenesis
Glucose Homeostasis
DNA Damage Response, Detection Of DNA Damage
Positive Regulation Of Apoptotic Process
Positive Regulation Of Gamma-delta T Cell Differentiation
Positive Regulation Of Translation
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription By RNA Polymerase II
Sympathetic Nervous System Development
Protein Stabilization
Limb Bud Formation
Ventricular Septum Morphogenesis
Negative Regulation Of Cell Death
Neuroepithelial Cell Differentiation
Kidney Morphogenesis
Hematopoietic Stem Cell Homeostasis
Cellular Response To Glucose Stimulus
Positive Regulation Of Canonical Wnt Signaling Pathway
Positive Regulation Of N-terminal Peptidyl-lysine Acetylation
Pathways
Deactivation of the beta-catenin transactivating complex
Drugs
Diseases
GWAS
Bone mineral density (
21533022
)
Cardiac hypertrophy (
21348951
)
Endometrial cancer (
30093612
27008869
)
Endometrial cancer (endometrioid histology) (
30093612
)
Metabolite levels (
23823483
)
Pulmonary function (smoking interaction) (
23284291
)
Interacting Genes
22 interacting genes:
ATF1
ATF2
CALM1
CALM2
CALM3
CDC42
CEBPA
CREB1
JUN
MAPK6
MEOX2
NR1H3
NR5A1
NR5A2
NRL
PPARG
PRKCA
RXRA
SOX4
TAF1
TBP
UBE2I
34 interacting genes:
AKT1
APOC3
AURKA
CAPN15
CDKN2A
CTR9
DACH1
EDF1
FOXH1
FZR1
IGF1
ITIH1
KRAS
MINPP1
MNT
MYC
NANOGNB
NF1
NF2
NSD3
PLD3
PLXNB1
RGSL1
RHOU
RP1L1
SCNN1G
SDCBP
SMARCA4
STK11
TERT
TNNI3
TSC1
UBE2I
WT1
Entrez ID
8721
6659
HPRD ID
09235
01695
Ensembl ID
ENSG00000107223
ENSG00000124766
Uniprot IDs
O60869
Q06945
PDB IDs
1X57
6ZVH
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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