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ACTN1 and DYNLT1
Data Source:
BioGRID
(two hybrid)
ACTN1
DYNLT1
Description
actinin alpha 1
dynein light chain Tctex-type 1
Image
GO Annotations
Cellular Component
Stress Fiber
Ruffle
Extracellular Region
Extracellular Space
Cytoplasm
Cytosol
Actin Filament
Plasma Membrane
Brush Border
Cell-cell Junction
Fascia Adherens
Focal Adhesion
Z Disc
Platelet Alpha Granule Lumen
Pseudopodium
Cell Projection
Extracellular Exosome
Glutamatergic Synapse
Extracellular Region
Mitochondrion
Golgi Apparatus
Spindle
Cytoplasmic Dynein Complex
Cytoplasmic Microtubule
Lamellipodium
Secretory Granule Lumen
Neuronal Cell Body
Host Cell
Axonal Growth Cone
Secretory Vesicle
Ficolin-1-rich Granule Lumen
Molecular Function
Double-stranded RNA Binding
Integrin Binding
Calcium Ion Binding
Protein Binding
Vinculin Binding
Nuclear Receptor Coactivator Activity
Protein Homodimerization Activity
Ion Channel Binding
Actin Filament Binding
Structural Constituent Of Postsynapse
Motor Activity
Protein Binding
Protein C-terminus Binding
Identical Protein Binding
Biological Process
Platelet Degranulation
Actin Filament Organization
Platelet Activation
Platelet Formation
Platelet Morphogenesis
Regulation Of Apoptotic Process
Positive Regulation Of Transcription, DNA-templated
Focal Adhesion Assembly
Actin Filament Bundle Assembly
Negative Regulation Of Cellular Component Movement
Actin Filament Network Formation
Platelet Aggregation
Postsynapse Organization
Establishment Of Mitotic Spindle Orientation
Regulation Of G Protein-coupled Receptor Signaling Pathway
Positive Regulation Of Neuron Projection Development
Dendrite Development
Intracellular Transport Of Viral Protein In Host Cell
Positive Regulation Of Rac Protein Signal Transduction
Negative Regulation Of Mitochondrial Membrane Permeability
Regulation Of GTPase Activity
Neutrophil Degranulation
Viral Entry Into Host Cell
Neuron Projection Morphogenesis
Negative Regulation Of Neurogenesis
Cell Division
Regulation Of Cytoskeleton Organization
Negative Regulation Of Cell Death
Axon Development
Microtubule-dependent Intracellular Transport Of Viral Material Towards Nucleus
Pathways
Platelet degranulation
Syndecan interactions
Nephrin family interactions
Regulation of cytoskeletal remodeling and cell spreading by IPP complex components
Neutrophil degranulation
Drugs
Human calcitonin
Copper
Diseases
GWAS
Asthma (
31959851
)
Cognitive decline rate in late mild cognitive impairment (
26252872
)
Feeling fed-up (
29500382
)
Feeling hurt (
29500382
)
Fibrinogen (
23969696
)
Fibrinogen levels (
28107422
)
High light scatter reticulocyte count (
32888494
)
Lack of perseverance (
30718321
)
Mean platelet volume (
32888494
27863252
)
Medication use (drugs used in diabetes) (
31015401
)
Mosquito bite size (
28199695
)
Neurociticism (
29500382
)
Periodontitis (Mean PAL) (
24024966
)
Platelet count (
26805783
29403010
32888494
)
Platelet distribution width (
32888494
27863252
)
Plateletcrit (
32888494
)
Prostate cancer (
23535732
)
Rheumatoid arthritis (ACPA-positive) (
23143596
)
Smoking behavior (
19247474
)
Urinary albumin excretion (
30220432
)
Interacting Genes
90 interacting genes:
ACTN2
ACTN3
ADORA2A
APC
APPBP2
ATXN2
ATXN7
C14orf119
CACNA1A
CAMK2A
CBY2
CDK5
CDK5R1
CDK5R2
CLIC5
COIL
COL17A1
CSRP1
CSRP3
CTNNA1
DDIAS
DYNLT1
EIF2S1
EPM2AIP1
ERBIN
FBP1
FXN
GADD45G
GFI1B
GIPC1
GIT2
GRIA4
GRIN2A
GRM5
GTF2H1
HSPB1
ICAM5
ITGB1
KAT2B
KCTD6
KPNA2
LINC01554
LNX1
LPP
MAGEA11
MAP2
MAP3K1
MED14
MICALL2
MTDH
MTNR1A
MTNR1B
MYOT
MYOZ1
MYOZ2
MYOZ3
NEBL
NKAPD1
NR1H3
NUMBL
OAS1
PALLD
PDHX
PDLIM1
PDLIM5
PIAS4
PKD1
PKN1
PLD2
PSEN1
PSMA1
PTK2
PTPN1
PTPN6
PYGB
RAVER1
RPS27
SIRPA
SLC2A4
SORBS2
SRC
SSX2IP
SYNPO2L
TES
TTN
TXN
USP2
VCL
XRCC4
ZYX
50 interacting genes:
ACOX2
ACTN1
APP
ARID4B
BAG3
BMPR2
CCDC68
DDX54
DHX33
DNAJA2
DOC2A
DOC2B
DVL1
DVL2
DYNC1I1
DYNC1I2
DYNLT2B
DYNLT3
FXR2
HAVCR1
HSPB7
HSPB9
ILF2
KIF2A
KLK15
LNX1
NHSL2
NTAQ1
NUP153
NUP62
OLFM3
PELO
PITX2
PSMA1
PTGES3L-AARSD1
PTH2R
PVR
RAD21
RBM14
RRAGA
SDCBP
SIRPA
SVIL
TCEANC
TROAP
TUBA3C
TXN
UXT
VDAC1
XRN2
Entrez ID
87
6993
HPRD ID
00020
15987
Ensembl ID
ENSG00000072110
ENSG00000146425
Uniprot IDs
A0A024R694
P12814
P63172
PDB IDs
2EYI
2EYN
2N8Y
2N8Z
5JPW
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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