DYNLT1 and DNAJA2

Data Source:
BioGRID (two hybrid)

		DYNLT1	DNAJA2
Description		dynein light chain Tctex-type 1	DnaJ heat shock protein family (Hsp40) member A2
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Mitochondrion Golgi Apparatus Spindle Cytoplasmic Dynein Complex Cytoplasmic Microtubule Lamellipodium Secretory Granule Lumen Neuronal Cell Body Host Cell Axonal Growth Cone Secretory Vesicle Ficolin-1-rich Granule Lumen	Cytosol Membrane Extracellular Exosome
	Molecular Function	Motor Activity Protein Binding Protein C-terminus Binding Identical Protein Binding	ATPase Activator Activity Protein Binding ATP Binding Heat Shock Protein Binding Metal Ion Binding Unfolded Protein Binding Chaperone Binding
	Biological Process	Establishment Of Mitotic Spindle Orientation Regulation Of G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Neuron Projection Development Dendrite Development Intracellular Transport Of Viral Protein In Host Cell Positive Regulation Of Rac Protein Signal Transduction Negative Regulation Of Mitochondrial Membrane Permeability Regulation Of GTPase Activity Neutrophil Degranulation Viral Entry Into Host Cell Neuron Projection Morphogenesis Negative Regulation Of Neurogenesis Cell Division Regulation Of Cytoskeleton Organization Negative Regulation Of Cell Death Axon Development Microtubule-dependent Intracellular Transport Of Viral Material Towards Nucleus	Positive Regulation Of Cell Population Proliferation Response To Heat Positive Regulation Of ATPase Activity Protein Refolding
Pathways		Neutrophil degranulation	HSP90 chaperone cycle for steroid hormone receptors (SHR)
Drugs
Diseases
GWAS			Factor VII activity ( 30642921)
Interacting Genes		50 interacting genes: ACOX2 ACTN1 APP ARID4B BAG3 BMPR2 CCDC68 DDX54 DHX33 DNAJA2 DOC2A DOC2B DVL1 DVL2 DYNC1I1 DYNC1I2 DYNLT2B DYNLT3 FXR2 HAVCR1 HSPB7 HSPB9 ILF2 KIF2A KLK15 LNX1 NHSL2 NTAQ1 NUP153 NUP62 OLFM3 PELO PITX2 PSMA1 PTGES3L-AARSD1 PTH2R PVR RAD21 RBM14 RRAGA SDCBP SIRPA SVIL TCEANC TROAP TUBA3C TXN UXT VDAC1 XRN2	5 interacting genes: DNAJB1 DYNLT1 ERG HSPA1A PTEN
Entrez ID		6993	10294
HPRD ID		15987	07105
Ensembl ID		ENSG00000146425	ENSG00000069345
Uniprot IDs		P63172	A0A024R6S1 O60884
PDB IDs		5JPW
Enriched GO Terms of Interacting Partners?
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