STX16 and VPS45

Data Source:
HPRD (two hybrid, in vitro)

		STX16	VPS45
Description		syntaxin 16	vacuolar protein sorting 45 homolog
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Cytoplasm Golgi Apparatus Trans-Golgi Network Cytosol Focal Adhesion Endomembrane System Integral Component Of Membrane Integral Component Of Synaptic Vesicle Membrane SNARE Complex Golgi Cisterna Trans-Golgi Network Membrane Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm	Golgi Membrane Cellular_component Golgi Apparatus Endosome Membrane Integral Component Of Membrane
	Molecular Function	SNARE Binding SNAP Receptor Activity Protein Binding Syntaxin Binding	Molecular_function Protein Binding
	Biological Process	Intracellular Protein Transport Vesicle Fusion Retrograde Transport, Endosome To Golgi Vesicle Docking Golgi Ribbon Formation	Intracellular Protein Transport Vesicle Docking Involved In Exocytosis Blood Coagulation Vesicle-mediated Transport
Pathways		Intra-Golgi traffic Retrograde transport at the Trans-Golgi-Network	Intra-Golgi traffic Factors involved in megakaryocyte development and platelet production
Drugs
Diseases		Pseudohypoparathyroidism
GWAS		Cardiovascular risk factors (age interaction) ( 20838585) Hemoglobin ( 32888494)	anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Bipolar disorder ( 31043756) Broad depression or schizophrenia ( 30626913) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Obesity in adult survivors of childhood cancer not exposed to cranial radiation ( 25963547) Refractive error ( 32231278) Schizophrenia ( 25056061 29483656) Uric acid levels ( 21294900)
Interacting Genes		14 interacting genes: MEOX2 NAPB PTPN12 RHOU SNAP29 STX1A STX2 STX4 STX6 VAMP3 VAMP4 VAMP5 VPS45 VTI1A	11 interacting genes: BCAR3 CASP8 IGF1R PAX2 PTPN1 RB1CC1 RBSN SNTG1 STX16 VPS11 VPS18
Entrez ID		8675	11311
HPRD ID		04718	10301
Ensembl ID		ENSG00000124222	ENSG00000136631
Uniprot IDs		B4DJX9 O14662	A0A2R8YE10 B7Z360 B7Z5D4 Q9NRW7
PDB IDs
Enriched GO Terms of Interacting Partners?
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