OASL and MBD1

Data Source:
HPRD (two hybrid, in vivo, in vitro)

		OASL	MBD1
Description		2'-5'-oligoadenylate synthetase like	methyl-CpG binding domain protein 1
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GO Annotations	Cellular Component	Nucleoplasm Nucleolus Cytoplasm Cytosol Membrane	Nucleus Nucleoplasm Chromosome Nuclear Matrix Nuclear Speck
	Molecular Function	2'-5'-oligoadenylate Synthetase Activity DNA Binding RNA Binding Double-stranded RNA Binding Protein Binding Thyroid Hormone Receptor Binding	DNA Binding Protein Binding Zinc Ion Binding Methyl-CpG Binding Double-stranded Methylated DNA Binding Unmethylated CpG Binding
	Biological Process	Response To Virus Negative Regulation Of Viral Genome Replication Defense Response To Virus Interferon-gamma-mediated Signaling Pathway Type I Interferon Signaling Pathway Regulation Of Ribonuclease Activity	Transcription By RNA Polymerase II Negative Regulation Of Transcription, DNA-templated
Pathways		Interferon gamma signaling OAS antiviral response Interferon alpha/beta signaling	SUMOylation of transcription cofactors
Drugs
Diseases
GWAS		C-reactive protein ( 22939635) C-reactive protein levels ( 24763700 30388399) Cardiovascular disease risk factors ( 21943158) Hematocrit ( 32888494) Hemoglobin ( 32888494) N-glycan levels ( 21908519 21203500) Serum metabolite levels ( 23093944) Type 2 diabetes ( 30054458)	Chronic lymphocytic leukemia ( 28165464)
Interacting Genes		3 interacting genes: MBD1 SEZ6L2 THRA	25 interacting genes: APP ATF7IP ATF7IP2 ATXN1L CBX4 CBX5 CHAF1A ECT2 HDAC3 HIPK3 HTT OASL PIAS1 PIAS2 RNF2 SETDB1 SMAD1 SMAD3 SMAD5 SMAD7 SMAD9 SP1 SUV39H1 TENM1 ZNF512B
Entrez ID		8638	4152
HPRD ID		04473	01133
Ensembl ID		ENSG00000135114	ENSG00000141644
Uniprot IDs		Q15646	A8K654 B4DI41 B4DUR3 Q9UIS9
PDB IDs		1WH3 4XQ7	1D9N 1IG4 4D4W 5W9Q 6D1T
Enriched GO Terms of Interacting Partners?
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