OASL and SEZ6L2

Data Source:
BioGRID (two hybrid)

		OASL	SEZ6L2
Description		2'-5'-oligoadenylate synthetase like	seizure related 6 homolog like 2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Nucleolus Cytoplasm Cytosol Membrane	Endoplasmic Reticulum Membrane Plasma Membrane Integral Component Of Membrane
	Molecular Function	2'-5'-oligoadenylate Synthetase Activity DNA Binding RNA Binding Double-stranded RNA Binding Protein Binding Thyroid Hormone Receptor Binding
	Biological Process	Response To Virus Negative Regulation Of Viral Genome Replication Defense Response To Virus Interferon-gamma-mediated Signaling Pathway Type I Interferon Signaling Pathway Regulation Of Ribonuclease Activity
Pathways		Interferon gamma signaling OAS antiviral response Interferon alpha/beta signaling
Drugs
Diseases
GWAS		C-reactive protein ( 22939635) C-reactive protein levels ( 24763700 30388399) Cardiovascular disease risk factors ( 21943158) Hematocrit ( 32888494) Hemoglobin ( 32888494) N-glycan levels ( 21908519 21203500) Serum metabolite levels ( 23093944) Type 2 diabetes ( 30054458)	Alcohol consumption ( 31358974) Alcohol consumption (drinks per week) ( 30643258) Anthropometric traits ( 19260139) Autism spectrum disorder or schizophrenia ( 28540026) Bitter alcoholic beverage consumption ( 31046077) Body fat distribution (arm fat ratio) ( 30664634) Response to taxane treatment (placlitaxel) ( 23006423) Schizophrenia ( 28991256 25056061 29483656) Systemic lupus erythematosus ( 23273568)
Interacting Genes		3 interacting genes: MBD1 SEZ6L2 THRA	7 interacting genes: ETV5 FOXA1 MTDH OASL TK1 TOX3 UNG
Entrez ID		8638	26470
HPRD ID		04473	06686
Ensembl ID		ENSG00000135114	ENSG00000174938
Uniprot IDs		Q15646	A0A087WYL5 A0A0A8K8P7 B7Z5L4 Q6UXD5
PDB IDs		1WH3 4XQ7
Enriched GO Terms of Interacting Partners?
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