ASMTL and TDO2

Data Source:
BioGRID (two hybrid, two hybrid, affinity chromatography technology, two hybrid, two hybrid)
HPRD (two hybrid)

		ASMTL	TDO2
Description		acetylserotonin O-methyltransferase like	tryptophan 2,3-dioxygenase
Image
GO Annotations	Cellular Component	Cytosol	Cytosol
	Molecular Function	Molecular_function Protein Binding O-methyltransferase Activity NADH Pyrophosphatase Activity DTTP Diphosphatase Activity Nucleoside-triphosphate Diphosphatase Activity	Tryptophan 2,3-dioxygenase Activity Protein Binding Amino Acid Binding Oxygen Binding Heme Binding Identical Protein Binding Metal Ion Binding
	Biological Process	Biological_process Nucleotide Metabolic Process Methylation	Tryptophan Catabolic Process Tryptophan Catabolic Process To Kynurenine Tryptophan Catabolic Process To Acetyl-CoA Protein Homotetramerization Response To Nitroglycerin
Pathways			Tryptophan catabolism
Drugs
Diseases
GWAS			Blood metabolite levels ( 24816252) Manganese levels ( 26025379) Speech perception in dyslexia ( 19786962)
Interacting Genes		10 interacting genes: APP GORASP2 HLA-DRB4 KRT31 KRT34 KRT40 PNMA1 REL TDO2 ZNF655	20 interacting genes: ASMTL DPM1 EIF4E KDM1A LMNA LNX1 MEOX2 MOB1A MOB3C NGB NMNAT1 NR1D1 PICK1 PM20D2 PRMT6 PSMA1 REL SDCBP SDCBP2 ZFYVE26
Entrez ID		8623	6999
HPRD ID		02156	01847
Ensembl ID		ENSG00000169093	ENSG00000151790
Uniprot IDs		B3KM43 O95671	P48775
PDB IDs		2P5X	4PW8 5TI9 5TIA 6A4I 6PYY 6PYZ 6VBN
Enriched GO Terms of Interacting Partners?
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