CADPS and AURKC

Data Source:
BioGRID (two hybrid)

		CADPS	AURKC
Description		calcium dependent secretion activator	aurora kinase C
Image
GO Annotations	Cellular Component	Cytosol Presynapse Glutamatergic Synapse Neuronal Dense Core Vesicle Membrane	Condensed Chromosome Nucleus Cytoplasm Spindle Spindle Microtubule Midbody Spindle Pole Centrosome Chromosome Passenger Complex Spindle Midzone
	Molecular Function	Protein Binding Lipid Binding Protein Kinase Binding Metal Ion Binding	Protein Kinase Activity Protein Serine/threonine/tyrosine Kinase Activity Protein Binding ATP Binding Histone Serine Kinase Activity Protein Serine Kinase Activity Protein Threonine Kinase Activity
	Biological Process	Exocytosis Protein Transport Synaptic Vesicle Exocytosis Positive Regulation Of Exocytosis Dense Core Granule Exocytosis	Protein Phosphorylation Mitotic Spindle Organization Spermatogenesis Attachment Of Spindle Microtubules To Kinetochore Histone Modification Regulation Of Cytokinesis Positive Regulation Of Cytokinesis Histone-serine Phosphorylation Oocyte Development Mitotic Spindle Midzone Assembly Cell Division Meiotic Cell Cycle
Pathways
Drugs		Calcium citrate Calcium Phosphate Calcium phosphate dihydrate	SNS-314 Fostamatinib
Diseases
GWAS		Adult body size ( 32376654) Autism spectrum disorder ( 30804558) Body size at age 10 ( 32376654) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Breast size ( 22747683 27182965) Cognitive decline rate in late mild cognitive impairment ( 26252872) Cortical surface area (MOSTest) ( 32665545) Economic and political preferences (environmentalism) ( 22566634) Fasting plasma glucose ( 31932636) Hand grip strength ( 29691431) Lung function (FEV1/FVC) ( 30061609) Meat-related diet ( 32066663) Metabolite levels (X-11787) ( 23934736) Obsessive-compulsive symptoms ( 26859814) Optic disc size ( 31809533) Pre-treatment viral load in HIV-1 infection ( 31219150) Processed meat consumption ( 32066663) QT interval (sulfonylurea treatment interaction) ( 27958378) Risk-taking tendency (4-domain principal component model) ( 30643258) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Systolic blood pressure x educational attainment (graduated college) interaction (2df) ( 32372009) Thiopurine-induced leukopenia in inflammatory bowel disease ( 29923122) Trunk fat mass ( 28552196)
Interacting Genes		43 interacting genes: ACTN3 ANKS1A AURKC C17orf67 CABP5 CCDC120 CCDC185 DMD DNAJC5 DRD2 FAM161A FAM90A1 FAM9B FANCL FOXD2 GADD45GIP1 GPANK1 GSE1 HDAC4 HOXB5 HOXC8 KANK2 KIAA1549 LNX1 LUC7L2 OLIG3 PIP5K1A PNMA5 PRPF18 SDCBP SEC23A SH2D4A SHFL TCL1A TENT2 TRIM55 TRIM63 TSEN2 TTLL10 USP2 ZFC3H1 ZNF572 ZNF688	13 interacting genes: BIRC5 BIRC7 BRCA1 CADPS CENPA H3C1 INCENP LNX1 NEDD4 NEDD4L OTX2 SRPK1 TACC2
Entrez ID		8618	6795
HPRD ID		05236	04605
Ensembl ID		ENSG00000163618	ENSG00000105146
Uniprot IDs		F1T0E5 Q9ULU8	Q9UQB9
PDB IDs		1WI1	6GR8 6GR9
Enriched GO Terms of Interacting Partners?
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