PLPP1 and SSMEM1

Data Source:
BioGRID (two hybrid)

		PLPP1	SSMEM1
Description		phospholipid phosphatase 1	serine rich single-pass membrane protein 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Caveola Membrane Apical Plasma Membrane Membrane Raft Extracellular Exosome	Integral Component Of Membrane
	Molecular Function	Diacylglycerol Diphosphate Phosphatase Activity Protein Binding Phosphatidate Phosphatase Activity Sphingosine-1-phosphate Phosphatase Activity Lipid Phosphatase Activity Ceramide-1-phosphate Phosphatase Activity	Protein Binding
	Biological Process	Phospholipid Metabolic Process Sphingosine Metabolic Process Ceramide Metabolic Process Signal Transduction Protein Kinase C-activating G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Cell Population Proliferation Regulation Of Lipid Metabolic Process Sphingolipid Biosynthetic Process Intracellular Steroid Hormone Receptor Signaling Pathway Androgen Receptor Signaling Pathway Phospholipid Dephosphorylation
Pathways		Sphingolipid de novo biosynthesis
Drugs
Diseases
GWAS		Cocaine dependence ( 31212010) Heel bone mineral density ( 30598549 28869591)	Neurological blood protein biomarker levels ( 31320639)
Interacting Genes		5 interacting genes: CREB3 FAHD1 FXYD1 GPR42 SSMEM1	95 interacting genes: ALG3 APOA2 AQP1 AQP10 AQP3 ATP6V0C BET1 BLCAP C11orf24 C1QL4 C4orf3 C5 CCL4L2 CDS2 CLRN2 CMTM7 CSGALNACT2 CTSA CXCL16 CXCL9 CYB561 CYBC1 DEFB103A DEFB103B DEFB121 EFNA5 EMD ERG28 ERMP1 FAM3C FATE1 FDPS FPR2 GJB2 GPHB5 GPR151 HMOX2 LAT LEPROTL1 LNPEP MARCHF2 MCRS1 MFSD12 MFSD5 MFSD6 MIP MMD2 MS4A13 NIPAL4 NRM PGAP2 PLPP1 PLPP4 PLPP6 PLPPR2 RHD RTP2 RUSF1 S1PR5 SERP1 SLC35A1 SLC35C2 SLC35E3 SLC38A1 SLC38A7 SLC39A2 SLC39A9 SLC41A1 SLC41A2 STX8 TAP1 TAS2R10 TLCD1 TM6SF2 TMEM128 TMEM14A TMEM14C TMEM203 TMEM218 TMEM222 TMEM239 TMEM243 TMEM45A TMEM60 TMEM86A TMEM86B TMEM97 TMPPE TNF TRARG1 UNC93B1 UPK1B VAMP4 YIPF6 ZFPL1
Entrez ID		8611	136263
HPRD ID		06178	14060
Ensembl ID		ENSG00000067113	ENSG00000165120
Uniprot IDs		A0A024QZS3 A0A024QZU7 O14494	A0A3B3ISA2 A4D1L0 Q8WWF3
PDB IDs
Enriched GO Terms of Interacting Partners?
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