STK16 and NBPF19

Data Source:
BioGRID (two hybrid)

		STK16	NBPF19
Description		serine/threonine kinase 16	NBPF member 19
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Golgi Apparatus Cytosol Plasma Membrane Perinuclear Region Of Cytoplasm	Cytoplasm
	Molecular Function	Protein Serine/threonine Kinase Activity Non-membrane Spanning Protein Tyrosine Kinase Activity Protein Binding ATP Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity
	Biological Process	Peptidyl-tyrosine Phosphorylation Protein Autophosphorylation
Pathways
Drugs		Fostamatinib
Diseases
GWAS		High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494)	Serum uric acid levels ( 30993211)
Interacting Genes		84 interacting genes: ADAMTSL4 AGR2 ARNT2 ATP23 BHLHA9 CALCOCO2 CBX3 CCDC33 CFP CRX CSKMT CSNK2B CYSRT1 DDIT4L DNAJA3 DRG1 EFEMP2 EFHC2 ELK1 FLACC1 FRS3 FXR1 GABPA IKZF3 INCA1 KCTD14 KCTD17 KLHL20 KPRP KRT31 KRTAP1-1 KRTAP1-3 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP11-1 KRTAP13-1 KRTAP13-2 KRTAP26-1 KRTAP6-3 MBP MEOX2 MGAT5B MIER3 MIIP MTUS2 NAA80 NAGK NBPF19 NIF3L1 NOTCH2NLA PCSK5 PKNOX2 PLA2G10 PLSCR1 PLSCR3 PRDM6 PRKAR1B PTH1R REL RFX6 RPIA RSPO4 SAXO1 SKIL SOCS2 SPRY2 SSC4D TCF12 TCF4 TLE5 TNFAIP1 TRAF3IP2 TRIM27 TRIM42 TRIP6 USP54 YPEL3 ZMAT1 ZNF330 ZNF343 ZNF774	223 interacting genes: ADAM12 ADAMTSL4 AGXT ALDH16A1 ALPP ANKS1A AQP1 ATG9A ATP5F1D BCAM BMP7 BRME1 CARHSP1 CATSPER1 CCER1 CD164 CELF5 CERK CHCHD3 CHIC2 CHRD CHRNG CNNM3 COL8A1 CREB5 CRH CRY2 CST2 CST9L CTNNBIP1 CTSZ CXCL16 CYHR1 CYP21A2 CYSRT1 DAGLB DALRD3 DBH DGKQ DHRS1 DMRT3 DOCK2 DRD5 EMC7 F10 FADS2 FAM221A FAM71C FAM90A1 FBXW5 FRS3 FTHL17 FZD10 GLP1R GLYAT GNE GSTP1 HAPLN2 HBA1 HBA2 HBZ HCK HHEX HOXA1 HOXB9 HOXC8 HPCAL1 HSPA12B ICAM4 IL10 INO80B INS ITGB2 ITGB4 ITGB5 JOSD1 KCNS2 KCTD15 KLHL38 KLK8 KPRP KRT83 KRTAP10-1 KRTAP10-10 KRTAP10-5 KRTAP10-8 KRTAP10-9 KRTAP12-1 KRTAP12-2 KRTAP12-3 KRTAP12-4 KRTAP13-2 KRTAP13-3 KRTAP13-4 KRTAP2-3 KRTAP2-4 KRTAP26-1 KRTAP4-11 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP5-11 KRTAP5-3 KRTAP5-4 KRTAP5-6 KRTAP5-9 KRTAP9-2 KRTAP9-3 KRTAP9-8 LCE1A LCE1B LCE1D LCE1E LCE1F LCE2B LCE2C LCE2D LCE3A LCE3C LCE3D LCE3E LCE4A LCE5A LMNTD2 LNX1 LRFN4 LYVE1 MACO1 MAPKBP1 MELTF MFSD13A MOS MRGBP MRPL40 MTA1 MXD3 MXI1 MYO15B MYPOP NECTIN2 NECTIN3 NEDD9 NMU NPDC1 NR1D2 NTM NTN4 OLFM2 OTX1 P2RX4 P2RX7 P2RY6 PCSK5 PGAP6 PHLDA1 PIGS PLEKHN1 PRF1 PRR35 PSMA1 PTK7 PTPMT1 PVR R3HDM2 RAB3IL1 RAMP3 RASD1 RECK RNF111 RPS19BP1 RTN4RL1 SCNM1 SEMA3B SEMA4C SHFL SLC22A5 SLC23A1 SLC43A2 SLC5A5 SLC6A20 SMCP SPATA24 SPATA8 SPG7 SPPL2C SPRY1 STAC STK16 TAPBPL TCAF1 THAP7 TLE5 TMEFF2 TMEM150A TMIE TNIP3 TNS2 TRAPPC14 TRIM42 TROAP TSPAN4 TTPA UTP23 UXT VASN WDR25 ZDHHC1 ZNF124 ZNF319 ZNF330 ZNF408 ZNF414 ZNF417 ZNF440 ZNF446 ZNF497 ZNF580 ZNF581 ZNF587 ZNF648 ZNF672 ZNF786 ZNF837
Entrez ID		8576	101060226
HPRD ID		05281
Ensembl ID		ENSG00000115661	ENSG00000271383
Uniprot IDs		B4DPS1 B8ZZI5 O75716
PDB IDs		2BUJ
Enriched GO Terms of Interacting Partners?
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