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NBPF19 and HBA2
Data Source:
BioGRID
(two hybrid)
NBPF19
HBA2
Description
NBPF member 19
hemoglobin subunit alpha 2
Image
No pdb structure
GO Annotations
Cellular Component
Cytoplasm
Extracellular Region
Extracellular Space
Cytosol
Hemoglobin Complex
Membrane
Cytosolic Small Ribosomal Subunit
Haptoglobin-hemoglobin Complex
Extracellular Exosome
Endocytic Vesicle Lumen
Blood Microparticle
Molecular Function
Peroxidase Activity
Oxygen Carrier Activity
Iron Ion Binding
Protein Binding
Oxygen Binding
Heme Binding
Haptoglobin Binding
Organic Acid Binding
Biological Process
Receptor-mediated Endocytosis
Positive Regulation Of Cell Death
Oxygen Transport
Bicarbonate Transport
Response To Hydrogen Peroxide
Hydrogen Peroxide Catabolic Process
Cellular Oxidant Detoxification
Pathways
Erythrocytes take up carbon dioxide and release oxygen
Erythrocytes take up oxygen and release carbon dioxide
Scavenging of heme from plasma
Drugs
Iron Dextran
Iron
Zinc
4-Carboxycinnamic Acid
Pentaerythritol tetranitrate
2-[(2-methoxy-5-methylphenoxy)methyl]pyridine
4-[(5-methoxy-2-methylphenoxy)methyl]pyridine
Sebacic acid
2-[4-({[(3,5-DICHLOROPHENYL)AMINO]CARBONYL}AMINO)PHENOXY]-2-METHYLPROPANOIC ACID
2,6-dicarboxynaphthalene
Efaproxiral
Trimesic acid
Nitrous acid
Copper
Ferric pyrophosphate
Sodium ferric gluconate complex
Ferrous sulfate anhydrous
Ferric pyrophosphate citrate
Zinc acetate
Ferrous gluconate
Ferrous succinate
Ferrous ascorbate
Ferrous fumarate
Ferrous glycine sulfate
Zinc chloride
Zinc sulfate, unspecified form
Voxelotor
Ferric derisomaltose
Diseases
Thalassemia; Alpha thalassemia; Beta thalassemia; Alpha thalassemia, X-linked (ATRX)
GWAS
Serum uric acid levels (
30993211
)
Body mass index (
26426971
)
Hemoglobin A1c levels (
31217584
)
Hemoglobin levels (
26366553
)
High light scatter reticulocyte count (
32888494
27863252
)
High light scatter reticulocyte percentage of red cells (
32888494
27863252
)
Mean corpuscular hemoglobin (
32888494
28453575
20139978
)
Mean corpuscular hemoglobin concentration (
32888494
31217584
)
Mean corpuscular volume (
32888494
)
Red cell distribution width (
27863252
)
Reticulocyte count (
32888494
27863252
)
Reticulocyte fraction of red cells (
32888494
27863252
)
Interacting Genes
223 interacting genes:
ADAM12
ADAMTSL4
AGXT
ALDH16A1
ALPP
ANKS1A
AQP1
ATG9A
ATP5F1D
BCAM
BMP7
BRME1
CARHSP1
CATSPER1
CCER1
CD164
CELF5
CERK
CHCHD3
CHIC2
CHRD
CHRNG
CNNM3
COL8A1
CREB5
CRH
CRY2
CST2
CST9L
CTNNBIP1
CTSZ
CXCL16
CYHR1
CYP21A2
CYSRT1
DAGLB
DALRD3
DBH
DGKQ
DHRS1
DMRT3
DOCK2
DRD5
EMC7
F10
FADS2
FAM221A
FAM71C
FAM90A1
FBXW5
FRS3
FTHL17
FZD10
GLP1R
GLYAT
GNE
GSTP1
HAPLN2
HBA1
HBA2
HBZ
HCK
HHEX
HOXA1
HOXB9
HOXC8
HPCAL1
HSPA12B
ICAM4
IL10
INO80B
INS
ITGB2
ITGB4
ITGB5
JOSD1
KCNS2
KCTD15
KLHL38
KLK8
KPRP
KRT83
KRTAP10-1
KRTAP10-10
KRTAP10-5
KRTAP10-8
KRTAP10-9
KRTAP12-1
KRTAP12-2
KRTAP12-3
KRTAP12-4
KRTAP13-2
KRTAP13-3
KRTAP13-4
KRTAP2-3
KRTAP2-4
KRTAP26-1
KRTAP4-11
KRTAP4-2
KRTAP4-4
KRTAP4-5
KRTAP5-11
KRTAP5-3
KRTAP5-4
KRTAP5-6
KRTAP5-9
KRTAP9-2
KRTAP9-3
KRTAP9-8
LCE1A
LCE1B
LCE1D
LCE1E
LCE1F
LCE2B
LCE2C
LCE2D
LCE3A
LCE3C
LCE3D
LCE3E
LCE4A
LCE5A
LMNTD2
LNX1
LRFN4
LYVE1
MACO1
MAPKBP1
MELTF
MFSD13A
MOS
MRGBP
MRPL40
MTA1
MXD3
MXI1
MYO15B
MYPOP
NECTIN2
NECTIN3
NEDD9
NMU
NPDC1
NR1D2
NTM
NTN4
OLFM2
OTX1
P2RX4
P2RX7
P2RY6
PCSK5
PGAP6
PHLDA1
PIGS
PLEKHN1
PRF1
PRR35
PSMA1
PTK7
PTPMT1
PVR
R3HDM2
RAB3IL1
RAMP3
RASD1
RECK
RNF111
RPS19BP1
RTN4RL1
SCNM1
SEMA3B
SEMA4C
SHFL
SLC22A5
SLC23A1
SLC43A2
SLC5A5
SLC6A20
SMCP
SPATA24
SPATA8
SPG7
SPPL2C
SPRY1
STAC
STK16
TAPBPL
TCAF1
THAP7
TLE5
TMEFF2
TMEM150A
TMIE
TNIP3
TNS2
TRAPPC14
TRIM42
TROAP
TSPAN4
TTPA
UTP23
UXT
VASN
WDR25
ZDHHC1
ZNF124
ZNF319
ZNF330
ZNF408
ZNF414
ZNF417
ZNF440
ZNF446
ZNF497
ZNF580
ZNF581
ZNF587
ZNF648
ZNF672
ZNF786
ZNF837
16 interacting genes:
AHSP
CCDC57
CPM
DNAJC5
HBB
HBD
HBE1
HBG2
HBQ1
KRT31
KRT34
KRT40
NBPF19
NOTCH2NLA
SPP1
UCHL5
Entrez ID
101060226
3040
HPRD ID
00785
Ensembl ID
ENSG00000271383
ENSG00000188536
Uniprot IDs
D1MGQ2
P69905
PDB IDs
1A00
1A01
1A0U
1A0Z
1A3N
1A3O
1A9W
1ABW
1ABY
1AJ9
1B86
1BAB
1BBB
1BIJ
1BUW
1BZ0
1BZ1
1BZZ
1C7B
1C7C
1C7D
1CLS
1CMY
1COH
1DKE
1DXT
1DXU
1DXV
1FDH
1FN3
1G9V
1GBU
1GBV
1GLI
1GZX
1HAB
1HAC
1HBA
1HBB
1HBS
1HCO
1HDB
1HGA
1HGB
1HGC
1HHO
1IRD
1J3Y
1J3Z
1J40
1J41
1J7S
1J7W
1J7Y
1JY7
1K0Y
1K1K
1KD2
1LFL
1LFQ
1LFT
1LFV
1LFY
1LFZ
1LJW
1M9P
1MKO
1NEJ
1NIH
1NQP
1O1I
1O1J
1O1K
1O1L
1O1M
1O1N
1O1O
1O1P
1QI8
1QSH
1QSI
1QXD
1QXE
1R1X
1R1Y
1RPS
1RQ3
1RQ4
1RQA
1RVW
1SDK
1SDL
1SHR
1SI4
1THB
1UIW
1VWT
1XXT
1XY0
1XYE
1XZ2
1XZ4
1XZ5
1XZ7
1XZU
1XZV
1Y01
1Y09
1Y0A
1Y0C
1Y0D
1Y0T
1Y0W
1Y22
1Y2Z
1Y31
1Y35
1Y45
1Y46
1Y4B
1Y4F
1Y4G
1Y4P
1Y4Q
1Y4R
1Y4V
1Y5F
1Y5J
1Y5K
1Y7C
1Y7D
1Y7G
1Y7Z
1Y83
1Y85
1Y8W
1YDZ
1YE0
1YE1
1YE2
1YEN
1YEO
1YEQ
1YEU
1YEV
1YFF
1YG5
1YGD
1YGF
1YH9
1YHE
1YHR
1YIE
1YIH
1YVQ
1YVT
1YZI
1Z8U
2D5Z
2D60
2DN1
2DN2
2DN3
2DXM
2H35
2HBC
2HBD
2HBE
2HBF
2HBS
2HCO
2HHB
2HHD
2HHE
2M6Z
2W6V
2W72
2YRS
3B75
3D17
3D7O
3DUT
3HHB
3HXN
3IA3
3IC0
3IC2
3KMF
3NL7
3NMM
3ODQ
3ONZ
3OO4
3OO5
3OVU
3P5Q
3QJB
3QJC
3QJD
3QJE
3R5I
3S48
3S65
3S66
3SZK
3WCP
3WHM
4FC3
4HHB
4IJ2
4L7Y
4M4A
4M4B
4MQC
4MQG
4MQH
4MQI
4MQJ
4MQK
4N7N
4N7O
4N7P
4N8T
4NI0
4NI1
4ROL
4ROM
4WJG
4X0L
4XS0
5E29
5E6E
5E83
5EE4
5HU6
5HY8
5JDO
5KDQ
5KSI
5KSJ
5NI1
5SW7
5U3I
5UCU
5UFJ
5URC
5VMM
5WOG
5WOH
5X2R
5X2S
5X2T
5X2U
6BB5
6BNR
6BWP
6BWU
6DI4
6HAL
6HBW
6HK2
6KA9
6KAE
6KAH
6KAI
6KAO
6KAP
6KAQ
6KAR
6KAS
6KAT
6KAU
6KAV
6KYE
6L5V
6L5W
6L5X
6L5Y
6LCW
6LCX
6NBC
6NBD
6NQ5
6TB2
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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