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KHSRP and HNRNPA1
Data Source:
BioGRID
(affinity chromatography technology, pull down, affinity chromatography technology)
KHSRP
HNRNPA1
Description
KH-type splicing regulatory protein
heterogeneous nuclear ribonucleoprotein A1
Image
GO Annotations
Cellular Component
Exosome (RNase Complex)
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Membrane
Nucleus
Nucleoplasm
Spliceosomal Complex
Cytoplasm
Membrane
Extracellular Exosome
Catalytic Step 2 Spliceosome
Ribonucleoprotein Complex
Molecular Function
DNA Binding
RNA Binding
MRNA Binding
Protein Binding
MRNA 3'-UTR AU-rich Region Binding
Single-stranded DNA Binding
RNA Binding
Single-stranded RNA Binding
Protein Binding
Protein Domain Specific Binding
MiRNA Binding
Pre-mRNA Binding
Telomeric Repeat-containing RNA Binding
G-rich Strand Telomeric DNA Binding
Biological Process
RNA Splicing, Via Transesterification Reactions
Regulation Of Transcription, DNA-templated
MRNA Processing
RNA Splicing
Regulation Of Gene Expression
MiRNA Metabolic Process
Negative Regulation Of Low-density Lipoprotein Particle Clearance
Regulation Of MRNA Stability
Negative Regulation Of Nitric Oxide Biosynthetic Process
MRNA Transport
Positive Regulation Of MRNA Catabolic Process
3'-UTR-mediated MRNA Destabilization
Cellular Response To Cytokine Stimulus
Regulation Of Alternative MRNA Splicing, Via Spliceosome
MRNA Splicing, Via Spliceosome
RNA Export From Nucleus
Fibroblast Growth Factor Receptor Signaling Pathway
Viral Process
RNA Metabolic Process
Negative Regulation Of Telomere Maintenance Via Telomerase
Positive Regulation Of Telomere Maintenance Via Telomerase
Cellular Response To Glucose Starvation
MRNA Transport
Nuclear Export
Import Into Nucleus
Cellular Response To Sodium Arsenite
Pathways
ATF4 activates genes in response to endoplasmic reticulum stress
KSRP (KHSRP) binds and destabilizes mRNA
KSRP (KHSRP) binds and destabilizes mRNA
FGFR2 alternative splicing
mRNA Splicing - Major Pathway
Processing of Capped Intron-Containing Pre-mRNA
Drugs
Resveratrol
Artenimol
Diseases
GWAS
Meat-related diet (
32066663
)
Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) (
26426971
)
Interacting Genes
14 interacting genes:
A1CF
APBB1
BACE1
EXOSC2
EXOSC3
GADD45A
GSK3B
HNRNPA1
HNRNPH1
KLHL12
PARN
PTBP2
STK3
UBE2I
114 interacting genes:
ABHD16A
APP
BCL2L1
CLK1
ERG
ESR1
FEN1
H3-4
H3C1
HIPK3
HMGA1
HNRNPH3
KHSRP
MIR1-1
MIR1-2
MIR106A
MIR106B
MIR107
MIR10B
MIR122
MIR128-1
MIR128-2
MIR138-1
MIR138-2
MIR140
MIR141
MIR143
MIR145
MIR155
MIR15A
MIR15B
MIR16-1
MIR16-2
MIR17
MIR18A
MIR18B
MIR199A1
MIR199A2
MIR19A
MIR19B1
MIR19B2
MIR200A
MIR200B
MIR200C
MIR205
MIR206
MIR20A
MIR20B
MIR21
MIR214
MIR221
MIR222
MIR25
MIR29A
MIR29B1
MIR29B2
MIR29C
MIR31
MIR34A
MIR34B
MIR34C
MIR363
MIR429
MIR451A
MIR7-1
MIR7-2
MIR7-3
MIR9-1
MIR9-2
MIR9-3
MIR92A1
MIR92A2
MIR93
MIR98
MIRLET7A1
MIRLET7A2
MIRLET7A3
MIRLET7B
MIRLET7C
MIRLET7D
MIRLET7E
MIRLET7F1
MIRLET7F2
MIRLET7G
MIRLET7I
NFKBIA
NR0B2
NR3C1
PABPN1
PHYHIP
PPIL1
PRKDC
PRMT1
PRMT2
PRMT3
PRRC2A
PTEN
RNF14
RPL21
RPS6KB2
SAFB
SNRNP200
SREK1
SRPK1
SRPK2
SUFU
TFEC
TNPO1
TRA2B
TRAF6
TSHR
TTF2
XIAP
XRN1
Entrez ID
8570
3178
HPRD ID
10350
01242
Ensembl ID
ENSG00000088247
ENSG00000135486
Uniprot IDs
Q92945
A0A024RAZ7
A0A024RB53
P09651
PDB IDs
2HH2
2HH3
2JVZ
2OPU
2OPV
4B8T
1HA1
1L3K
1PGZ
1PO6
1U1K
1U1L
1U1M
1U1N
1U1O
1U1P
1U1Q
1U1R
1UP1
2H4M
2LYV
2UP1
4YOE
5MPG
5MPL
5ZGD
5ZGL
6BXX
6DCL
6J60
Enriched GO Terms of Interacting Partners
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