HAT1 and KANK4

Data Source:
BioGRID (two hybrid)

		HAT1	KANK4
Description		histone acetyltransferase 1	KN motif and ankyrin repeat domains 4
Image			No pdb structure
GO Annotations	Cellular Component	Chromosome, Telomeric Region Chromatin Nucleus Nucleoplasm Cytoplasm Nuclear Matrix Protein-containing Complex	Cytoplasm Cytosol Cytoskeleton Microtubule Cytoskeleton
	Molecular Function	Histone Acetyltransferase Activity Protein Binding H4 Histone Acetyltransferase Activity Histone Binding	Protein Binding
	Biological Process	DNA Packaging DNA Replication-dependent Nucleosome Assembly DNA Replication-independent Nucleosome Assembly Chromatin Silencing At Telomere Internal Protein Amino Acid Acetylation Response To Nutrient Histone H4 Acetylation	Negative Regulation Of Actin Filament Polymerization
Pathways		HATs acetylate histones
Drugs
Diseases
GWAS		Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Myopia ( 27182965) Refractive error ( 32231278) Spherical equivalent or myopia (age of diagnosis) ( 29808027)	Fuchs's corneal dystrophy ( 28358029) Regular attendance at a gym or sports club ( 29970889)
Interacting Genes		23 interacting genes: ACAA1 H2AC20 H3-4 H3C1 H4-16 H4C1 H4C14 HTR2B KANK4 MEOX2 MORN5 PRKAA2 RBBP4 REL SMAD7 SNAPC1 STEEP1 TCF4 TEPSIN TNFAIP1 TRIB3 YWHAQ ZSCAN4	6 interacting genes: CSK CUL5 HAT1 HOMER3 MYLIP TRAPPC6A
Entrez ID		8520	163782
HPRD ID		04339	14109
Ensembl ID		ENSG00000128708	ENSG00000132854
Uniprot IDs		O14929	B1ALP6 Q5T7N3
PDB IDs		2P0W 6VO5
Enriched GO Terms of Interacting Partners?
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